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Effect of simulated weightlessness on pressure-volume relationships of femoral veins in vivo of New-Zealand rabbits.

作者信息

Yao Yong-Jie, Yue Yong, Wu Xing-Yu

机构信息

Department of Aerospace Medicine, Fourth Military Medical University, Xi'an, China.

出版信息

J Gravit Physiol. 2002 Jul;9(1):P81-2.

PMID:14977003
Abstract

OBJECTIVES

To observe the change of pressure-volume relationships of femoral veins of rabbits after simulated weightlessness.

METHODS

Head-down tilt(HDT) -20 degrees rabbit model was used to simulate weightlessness .24 healthy male New-Zealand Rabbits were randomly divided into 21d HDT group, 10d HDT group and control group, with 8 in each. The pressure-volume relationships of rabbits femoral veins were measured.

RESULT

The femoral vein P-V relationship curves of HDT groups were shifted to larger volume change ratio than that of control group. The P-V relationship curve of the 21d HDT group was shifted more obviously than that of HDT-10d. B1 and B2 in quadratic equations of 21d HDT group were significantly higher than these value of 10d HDT group and control group during expansion (inflow) and collapse (outflow) (P<0.01).

CONCLUSIONS

The femoral venous compliance increased after weightlessness simulation and the femoral venous compliance of 21d-HDT increased more obviously than that of 10d-HDT.

摘要

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