Ito Toshiki, Nagae Hiroshi, Maruyama Satoshi, Hadano Shinsuke, Mugiya Soichi, Suzuki Kazuo, Ozono Seiichiro
Department of Urology, Seirei Mikatahara General Hospital.
Hinyokika Kiyo. 2003 Dec;49(12):765-70.
We report two cases of chromophobe cell renal carcinoma. Case 1 was in a 62-year-old man with the chief complaint of hematospermia. Ultrasound incidentally detected a left renal mass. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a relatively homogeneous, hypovascular tumor of the left kidney. We performed radical nephrectomy after making a clinical diagnosis of possible renal carcinoma. Case 2 was in a 66-year-old woman who was admitted to our hospital after a left renal mass was incidentally found by ultrasonography during a health check. We performed laparoscopic radical nephrectomy after making a diagnosis of renal cell carcinoma by CT and MRI. Both of the tumors were shown to be chromophobe cell carcinoma by microscopic examination after H & E staining and immunohistochemistry using Hale's colloidal iron stain. Chromophobe cell carcinoma is an uncommon type of renal cell carcinoma and the number of reported cases is limited in Japan. The clinical features and management of this rare tumor are discussed.
我们报告两例嫌色细胞肾细胞癌。病例1为一名62岁男性,主诉为血精。超声偶然发现左肾肿物。计算机断层扫描(CT)和磁共振成像(MRI)显示左肾有一个相对均匀、血供较少的肿瘤。在临床诊断可能为肾癌后,我们进行了根治性肾切除术。病例2为一名66岁女性,在健康检查期间超声偶然发现左肾肿物后入住我院。经CT和MRI诊断为肾细胞癌后,我们进行了腹腔镜根治性肾切除术。经苏木精-伊红(H&E)染色及使用黑尔胶体铁染色的免疫组织化学检查,显微镜检查显示两个肿瘤均为嫌色细胞癌。嫌色细胞癌是肾细胞癌的一种罕见类型,在日本报告的病例数量有限。本文讨论了这种罕见肿瘤的临床特征及治疗方法。