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[血红蛋白碳氧水平测定在长期低环境浓度一氧化碳暴露中的应用。一组暴露工人的研究]

[Usefulness of HbCO level determination in chronic exposure to low environmental concentrations of CO. Study of a group of exposed workers].

作者信息

La Paglia G, Di Venti E, Mangione G, Bodanza I, Gullo F, Scelsa D, Torretta R

机构信息

Cattedra di Igiene Industriale-Università degli Studi di Palermo.

出版信息

G Ital Med Lav Ergon. 2003 Jul-Sep;25 Suppl(3):57-8.

Abstract

This research is based on consideration that HbCO sampling, routinely effected on environmental physician demand for workers' biological monitoring, has a low significance. To confirm or reject this statement, we considered two population groups: n. 583 exposed workers and n. 334 not exposed subjects as control group. The habit of smoking (either as number of cigarettes or as time elapsed between the drawn and the last smoked cigarette) was obviously considered on both groups. The results have shown that it isn't possible to acknowledge the effect of a low CO occupational pollution by using HbCO haematic sampling. The A.A. affirm that it's due to low pollution level in work place and to wrong praxis of haematic sampling performed after a long time from the end of working turn. The research showed a direct correlation between HbCO level and smoking habit and a strong association between time elapsed from last smoked cigarette and haematic sampling.

摘要

本研究基于这样的考虑

应环境医师对工人进行生物监测的要求而常规进行的碳氧血红蛋白(HbCO)采样意义不大。为了证实或反驳这一说法,我们考虑了两组人群:583名暴露工人和作为对照组的334名未暴露受试者。两组都明显考虑了吸烟习惯(以吸烟数量或最后一支烟与当前吸烟之间的时间间隔来衡量)。结果表明,通过碳氧血红蛋白血液采样无法确认低浓度一氧化碳职业污染的影响。研究团队认为,这是由于工作场所污染水平较低以及工作轮次结束很长时间后进行血液采样的错误做法所致。该研究表明碳氧血红蛋白水平与吸烟习惯之间存在直接关联,且最后一支烟与血液采样之间的时间间隔与血液采样之间存在很强的关联。

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