García Ruiz P J, Rojo A, Sanchez Bernardos V, Romero A, Cubo E, Aguilar M
Servicios de Neurología, Fundación Jiménez Díaz, Madrid, Spain.
Neurologia. 2004 Mar;19(2):77-9.
Parkinson's disease (PD) is frequently associated with freezing of gait. Patients with advanced PD learn to use tricks to relieve freezing of gait. Recently one of our patients informed us that he could overcome freezing of gait by crawling. Since crawling is a sort of quadruped gait that humans develop transiently, we wondered whether quadruped gait is preserved in PD. We recruited 16 patients with PD who had frequent and disabling freezing of gait. Under experimental conditions, after 12 hours without medication, seven patients developed biped freezing of gait. Of these seven patients, only two patients (the patients with the most severe freezing) also developed quadruped freezing of gait. This experiment suggests that bipedal gait is affected early in PD, while quadruped gait is preserved until late in this disease.
帕金森病(PD)常与步态冻结相关。晚期帕金森病患者学会运用技巧来缓解步态冻结。最近,我们的一位患者告知我们,他可以通过爬行来克服步态冻结。由于爬行是人类短暂发展出的一种四足步态,我们想知道帕金森病患者是否保留了四足步态。我们招募了16名患有频繁且致残性步态冻结的帕金森病患者。在实验条件下,在未服药12小时后,7名患者出现双足步态冻结。在这7名患者中,只有两名患者(步态冻结最严重的患者)也出现了四足步态冻结。该实验表明,双足步态在帕金森病早期就受到影响,而四足步态在该病晚期仍得以保留。