Starska Katarzyna, Ciechomska Elzbieta A, Łukomski Marek
Katedra Otolaryngologii i Klinika Laryngologii UM w Łodzi.
Otolaryngol Pol. 2003;57(5):667-73.
In modern oncology quality of life (QL) in patients treated for neoplasmatic disease, has become a parameter of equal importance to other values of treatment success, such as 5-years survival, mean survival and disease free survival. The presence of cervical adenopathy and qualification for total laryngeal surgery and radical neck dissection is a source of deep additional mental experiences in patients with laryngeal carcinoma. The aim of this study was the objective establishment of QL in 70 patients treated in ENT Department University Medical in Łódź who underwent total laryngectomy and radical neck dissection, estimation of QL in various phases after treatment (in period of 6 months, from 6 to 12 months, and 1 year after surgery) and comparison of QL of patients after laryngeal surgery and QL of patients after surgery and radiotherapy. In order to evaluate quality of life the EOTRC QLQ-30, EOPRTC QLQ-H&N35 and HAD scale were used. It was stated, that the most difficult time for patients after radical neck dissection is the first 6 months after surgery, and the quality of life in patients after surgery and radiotherapy was lower than that of other patients in period of observation.
在现代肿瘤学中,接受肿瘤疾病治疗的患者的生活质量(QL)已成为与其他治疗成功指标同等重要的参数,如5年生存率、平均生存期和无病生存期。颈部淋巴结肿大以及全喉手术和根治性颈清扫术的资格认定是喉癌患者深度额外心理体验的来源。本研究的目的是客观确定在罗兹大学医学院耳鼻喉科接受全喉切除术和根治性颈清扫术的70例患者的生活质量,评估治疗后各阶段(术后6个月、6至12个月以及术后1年)的生活质量,并比较喉癌手术后患者的生活质量与手术联合放疗后患者的生活质量。为了评估生活质量,使用了欧洲癌症研究与治疗组织生活质量核心问卷30(EOTRC QLQ - 30)、欧洲癌症研究与治疗组织头颈癌特异性问卷(EOPRTC QLQ - H&N35)和医院焦虑抑郁量表(HAD scale)。结果表明,根治性颈清扫术后患者最困难的时期是术后的前6个月,并且在观察期内,手术联合放疗患者的生活质量低于其他患者。