心房颤动的管理概述：当前的技术水平如何？

Overview of the management of atrial fibrillation: what is the current state of the art?

作者信息

Kowey Peter R, Yan Gan-Xin, Dimino Tara L, Kocovic Dusan Z

机构信息

Cardiovascular Division, Lankenau Hospital and Medical Research Center, and the Main Line Health Heart Center, Wynnewood, Pennsylvania 19096, USA.

出版信息

J Cardiovasc Electrophysiol. 2003 Dec;14(12 Suppl):S275-80; discussion S280. doi: 10.1046/j.1540-8167.2003.90405.x.

DOI:10.1046/j.1540-8167.2003.90405.x

PMID:15005214

Abstract

Management of Atrial Fibrillation. There are three fundamental approaches to the management of atrial fibrillation (AF): rate control, rhythm control, and anticoagulation. Selecting a course of treatment requires a thorough knowledge of these therapeutic alternatives. This article explores treatment options, including the relative benefits of rate control versus rhythm control, which are complicated by the lack of highly effective and safe antiarrhythmic drugs. Anticoagulation is also an important issue in AF management, and warfarin effectively reduces the incidence of thromboembolic events in AF patients. The use of warfarin, however, presents its own complications. We conclude that individualization of therapy is paramount when treating AF.

摘要

心房颤动的管理。心房颤动（AF）的管理有三种基本方法：心率控制、节律控制和抗凝。选择治疗方案需要对这些治疗选择有全面的了解。本文探讨了治疗方案，包括心率控制与节律控制的相对益处，由于缺乏高效且安全的抗心律失常药物，这两种方法变得复杂。抗凝也是心房颤动管理中的一个重要问题，华法林可有效降低心房颤动患者血栓栓塞事件的发生率。然而，使用华法林也有其自身的并发症。我们得出结论，治疗心房颤动时，个体化治疗至关重要。