Engström Christer, Brändström Sven, Sigvardsson Sören, Cloninger C Robert, Nylander Per-Olof
Department of Neuroscience and Locomotion, University of Linköping, Linköping, Sweden.
Bipolar Disord. 2004 Apr;6(2):130-8. doi: 10.1111/j.1399-5618.2004.00101.x.
The aim of the study was to examine whether personality, i.e. temperament and character influence suicide attempts in bipolar patients.
Bipolar patients were recruited from lithium dispensaries. Temperament and character inventory (TCI) was administered to 100 euthymic bipolar patients and 100 controls.
Age of onset was significantly lower in patients with suicide attempts in the total bipolar group (I and II) and bipolar I patients compared with patients without suicide attempts. Bipolar (I and II) and bipolar I patients with suicide attempts were significantly higher in harm avoidance (HA) and reward dependence compared with patients without suicide attempts. Patients (I and II) with suicide attempts had significantly more anticipatory worry, fatigability and asthenia than patients without suicide attempts. Bipolar I patients with suicide attempts had significantly more fatigability and asthenia and were more dependent than patients without suicide attempts. HA was lowest in patients with no suicide attempts and no family history of suicide, higher in patients with family history of suicide or patients with suicide attempts, and significantly highest in patients with suicide attempts and family history of suicide. Patients with suicide attempts and family history of suicide had more anticipatory worry, fatigability and asthenia. Bipolar disorder was significantly correlated to HA and suicide attempts to HA and PS. Family history of suicide and gender were significantly correlated to suicide attempts.
Age of onset, HA, PS, gender and family history of suicide had a moderate to very strong effect on suicide attempts in bipolar patients.
本研究旨在探讨人格，即气质和性格是否会影响双相情感障碍患者的自杀未遂行为。
从锂盐药房招募双相情感障碍患者。对100名心境正常的双相情感障碍患者和100名对照者进行气质和性格量表（TCI）测试。
在整个双相情感障碍组（I型和II型）以及双相I型患者中，有自杀未遂行为的患者起病年龄显著低于无自杀未遂行为的患者。有自杀未遂行为的双相情感障碍（I型和II型）及双相I型患者在回避伤害（HA）和奖赏依赖方面显著高于无自杀未遂行为的患者。有自杀未遂行为的患者（I型和II型）比无自杀未遂行为的患者有更多的预期性担忧、易疲劳和乏力。有自杀未遂行为的双相I型患者比无自杀未遂行为的患者有更多的易疲劳和乏力，且更依赖他人。在无自杀未遂行为且无自杀家族史的患者中HA最低，在有自杀家族史或有自杀未遂行为的患者中HA较高，而在有自杀未遂行为且有自杀家族史的患者中HA显著最高。有自杀未遂行为且有自杀家族史的患者有更多的预期性担忧、易疲劳和乏力。双相情感障碍与HA显著相关，自杀未遂与HA和PS显著相关。自杀家族史和性别与自杀未遂显著相关。
起病年龄、HA、PS、性别和自杀家族史对双相情感障碍患者的自杀未遂行为有中度至非常强的影响。
