Kaneko Junichi, Sugawara Yasuhiko, Akamatsu Nobuhisa, Kokudo Norihiro, Makuuchi Masatoshi
Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan.
Hepatogastroenterology. 2004 Jan-Feb;51(55):262-3.
BACKGROUND/AIMS: The purpose of the present study was to examine the changes of spleen volume and platelet numbers after living donor liver transplantation in adults.
The spleen volume was measured by computed tomography preoperatively and 1, 6, and 12 months in 19 patients after liver transplantation. The platelet numbers were followed on the same time schedule.
The preoperative average spleen volume was 451+/-276 mL, which decreased gradually after liver transplantation. The preoperative averaged platelet number was 15.4+/-9.0x10(4)/mL, which did not change significantly during the observation period.
The changes in spleen volume in the present study were consistent with the previous data, suggesting that living donor liver transplantation effectively reduced hypersplenism for adult patients.
背景/目的：本研究旨在探讨成人活体肝移植术后脾脏体积和血小板数量的变化。
对19例肝移植患者在术前、术后1个月、6个月和12个月通过计算机断层扫描测量脾脏体积，并在相同时间点跟踪血小板数量。
术前脾脏平均体积为451±276 mL，肝移植后逐渐减小。术前血小板平均数量为15.4±9.0×10⁴/mL，在观察期内无明显变化。
本研究中脾脏体积的变化与先前数据一致，提示活体肝移植可有效减轻成年患者的脾功能亢进。
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