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免疫表型分析在B细胞淋巴增殖性疾病诊断中的重要性

[Importance of immunophenotyping in the diagnosis of B-cell lymphoproliferative diseases ].

作者信息

Prausová D, Krejsek J, Zák P, Voglová J, Belada D

机构信息

Ustav klinické imunologie a alergologie Lékarské fakulty UK a FN, Hradec Králové.

出版信息

Vnitr Lek. 2004 Jan;50(1):45-53.

Abstract

The immunophenotyping of the lymphoproliferative diseases is considered to be an integral part of the diagnostic process pointing to the correct classification of the individual diseases and to the choice of the most suitable type of therapy. This article describes the immunophenotype of particular types of B-lymphoproliferative disorders included in the World Health Organization classification (WHO) and the prognostic importance of some markers. The panel of specific monoclonal antibodies directed to B-cell lineage used in our department is displayed.

摘要

淋巴增殖性疾病的免疫表型分析被认为是诊断过程中不可或缺的一部分,有助于对个体疾病进行正确分类,并选择最合适的治疗类型。本文描述了世界卫生组织(WHO)分类中特定类型B淋巴细胞增殖性疾病的免疫表型以及一些标志物的预后重要性。展示了我们科室使用的针对B细胞谱系的特异性单克隆抗体组合。

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