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乳腺癌治疗病例中对侧乳房筛查的三联法

Triple approach method for screening of contralateral breast in treated cases of breast cancer.

作者信息

Deshpande Archana H, Munshi Maitreyee, Gaikwad Saroj, Deshpande Kamayani M

机构信息

Department of Pathology, Government Medical College, Nagpur, Maharashtra, India.

出版信息

Indian J Pathol Microbiol. 2003 Jul;46(3):385-9.

Abstract

A prospective study of 50 cases of treated breast cancer was undertaken to evaluate the status of the contralateral breast by combined physical examination, mammographic screening and mammographically directed FNAB (triple approach method). This study was done to assess the frequency of synchronous (cancers that were simultaneously diagnosed with a tumour in ipsilateral breast) or metachronous (those that occurred in contralateral breast subsequent to first cancer and not detected at the time of treatment of first cancer) malignancy and/or presence of preneoplastic lesions in the contralateral breast. Six percent cases had palpable lump in contralateral breast (synchronous or metachronous), 10% of the cases showed mammographic abnormalities. Mammographically directed FNAB showed atypical/suspicious smears in 8% cases and malignancy in 2% cases, of which infiltrating duct carcinoma was the most frequent. In high-risk group patients triple approach method proved to be extremely important screening procedure for early detection of abnormalities in contralateral breast and helps in significantly reducing the morbidity and mortality associated with it.

摘要

对50例接受治疗的乳腺癌患者进行了一项前瞻性研究,通过体格检查、乳腺钼靶筛查和乳腺钼靶引导下的细针穿刺抽吸活检(三联法)来评估对侧乳房的状况。开展这项研究是为了评估同步性(与同侧乳房肿瘤同时诊断出的癌症)或异时性(在首次癌症之后发生于对侧乳房且在首次癌症治疗时未被检测到的癌症)恶性肿瘤和/或对侧乳房中癌前病变的存在频率。6%的病例对侧乳房可触及肿块(同步性或异时性),10%的病例显示乳腺钼靶异常。乳腺钼靶引导下的细针穿刺抽吸活检显示8%的病例涂片不典型/可疑,2%的病例为恶性,其中浸润性导管癌最为常见。在高危组患者中,三联法被证明是早期发现对侧乳房异常的极其重要的筛查程序,有助于显著降低与之相关的发病率和死亡率。

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