Lieberman Jay R
Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Clin Orthop Relat Res. 2004 Jan(418):29-33. doi: 10.1097/00003086-200401000-00006.
The ultimate goal of treatment of patients with osteonecrosis of the hip is preservation of the femoral head. However, the development of a successful strategy to treat this disease has been difficult because neither the etiology nor the natural history of osteonecrosis of the hip has been defined clearly. Core decompression of the hip is one of the most commonly done surgical procedures to treat the early stages of osteonecrosis of the femoral head. However, there is no general consensus among investigators regarding either the specific indications for this procedure, or the specific technique of core decompression that would optimize results. The data available suggest that core decompression is more effective than nonoperative treatment particularly for patients with limited involvement of the femoral head and with an area of sclerosis surrounding the necrotic bone. The combination of core decompression with the use of osteoinductive or angiogenic agents to enhance bone formation and repair may enhance the results of this surgical procedure in the future.
髋关节骨坏死患者治疗的最终目标是保留股骨头。然而,由于髋关节骨坏死的病因和自然病史均未明确界定,因此制定一种成功治疗该疾病的策略一直很困难。髋关节核心减压术是治疗股骨头坏死早期阶段最常用的外科手术之一。然而,研究人员对于该手术的具体适应症以及能优化手术效果的核心减压具体技术,尚未达成普遍共识。现有数据表明,核心减压术比非手术治疗更有效,特别是对于股骨头受累有限且坏死骨周围有硬化区域的患者。未来,核心减压术与使用骨诱导或血管生成剂相结合以促进骨形成和修复,可能会提高该外科手术的效果。