Hashmi M A, Norman P, Saleh M
University of Sheffield, England, UK.
J Bone Joint Surg Br. 2004 Mar;86(2):269-75. doi: 10.1302/0301-620x.86b2.14011.
We describe our medium-term results for the management of chronic osteomyelitis in long bones using the Lautenbach procedure. Seventeen consecutive patients (18 segments) were treated prospectively. Osteomyelitis had been present for a mean of 12.5 years (1 to 31). A discharging sinus was present in all cases. Nine of the associated fractures had failed to unite and a further two needed correction of malunion. The Lautenbach procedure involves debridement, intramedullary reaming and the insertion of double-lumen tubes to establish both a local antibiotic delivery system and cavity analysis for volume and culture. The end-point of treatment is when the irrigate produces three consecutive clear cultures with improvement in the blood indices and obliteration of the cavity volume. The mean length of treatment was 27 days (14 to 48). One patient required a second procedure and another local debridement for recurrence of the infection. Two patients had Papineau grafting because of cortical defects. All the patients have subsequently remained free from infection. After treatment 11 had internal or external fixation for treatment of non- or malunion or a joint replacement, including two successful limb-lengthening procedures. Two further patients, while cured of infection, underwent amputation for other reasons. The mean length of follow-up was 75 months. This procedure allows precise control over the osteomyelitis until objective assessment suggests that infection has been cleared and the cavity obliterated. We recommend this procedure for long-standing complex cases in which basic techniques using debridement and antibiotics have failed.
我们描述了使用劳滕巴赫手术治疗长骨慢性骨髓炎的中期结果。对连续17例患者(18个节段)进行了前瞻性治疗。骨髓炎平均存在12.5年(1至31年)。所有病例均有引流窦。9例相关骨折未愈合,另外2例需要矫正畸形愈合。劳滕巴赫手术包括清创、髓内扩髓以及插入双腔管,以建立局部抗生素输送系统并进行腔隙容量和培养的分析。治疗终点是冲洗液连续三次培养结果呈阴性,血液指标改善且腔隙容积消失。平均治疗时长为27天(14至48天)。1例患者需要进行第二次手术,另1例因感染复发进行了局部清创。2例患者因皮质缺损接受了帕皮诺植骨术。所有患者随后均未再发生感染。治疗后,11例患者因治疗骨不连或畸形愈合或进行关节置换而接受了内固定或外固定,包括2例成功的肢体延长手术。另有2例患者虽感染治愈,但因其他原因接受了截肢手术。平均随访时长为75个月。该手术可精确控制骨髓炎,直至客观评估表明感染已清除且腔隙消失。对于清创和使用抗生素等基本技术治疗失败的长期复杂病例,我们推荐此手术。