孕期球囊二尖瓣成形术。

Balloon mitral valvuloplasty during pregnancy.

作者信息

Routray S N, Mishra T K, Swain S, Patnaik U K, Behera M

机构信息

Department of Cardiology, SCB Medical College, Cuttack, Orissa, India.

出版信息

Int J Gynaecol Obstet. 2004 Apr;85(1):18-23. doi: 10.1016/j.ijgo.2003.09.005.

DOI:10.1016/j.ijgo.2003.09.005

PMID:15050462

Abstract

OBJECTIVES

Balloon mitral valvuloplasty (BMV) has been performed safely during pregnancy with good results. Reports are few on long-term effects of BMV on childhood development.

METHODS

BMV was performed in 40 pregnant women (age 23.4+/-4.8 years) with severe mitral stenosis at 24.2+/-4.6 weeks of gestation.

RESULTS

Mitral valve area increased from 0.82+/-0.34 to 1.9+/-0.4 cm(2) (P<0.001). One patient had pericardial tamponade. Mean fluoroscopy time was 5.5+/-3.8 min. There was no maternal death, no abortion, no intrauterine growth restriction and one stillbirth. All 39 babies were normal at birth. One baby died at 7 months due to pneumonia. On follow up for 36+/-15 months, all 38 babies maintained normal growth and development without any thyroid disease or malignancy.

CONCLUSIONS

During pregnancy BMV is feasible, safe and effective. Maternal and fetal outcomes are excellent. Growth and milestone of development are not affected.

摘要

目的

在孕期安全地进行了球囊二尖瓣成形术（BMV），效果良好。关于BMV对儿童发育的长期影响的报道较少。

方法

对40名妊娠24.2±4.6周的重度二尖瓣狭窄孕妇（年龄23.4±4.8岁）进行了BMV。

结果

二尖瓣瓣口面积从0.82±0.34增加至1.9±0.4 cm²（P<0.001）。1例患者发生心包填塞。平均透视时间为5.5±3.8分钟。无孕产妇死亡、无流产、无胎儿生长受限，1例死产。39例婴儿出生时均正常。1例婴儿7个月时因肺炎死亡。随访36±15个月，38例婴儿均生长发育正常，无任何甲状腺疾病或恶性肿瘤。