Modrzyński Marek, Zawisza Edward, Rapiejko Piotr, Przybylski Grzegorz, Lipiec Agnieszka, Królikiewicz Janusz
Poradnia Alergologiczna NZOZ Euromedica 86-300 Grudziadz, ul. Chełmska 74.
Przegl Lek. 2003;60(10):633-6.
Allergic sensitisation of the airways occurs in the mucosa of the shock organ, or in the lymphatic stations draining these structures. The lymphatic structure closest to the nasal mucosa in humans is the adenoid. Pediatric adenoidal obstruction of the nasal airway is associated with significant morbidity and is a frequent indication for surgery. Because efficacious medical alternatives to adenoidectomy are lacking, we assessed the potency of standard-dose topical nasal fluticasone propionate and Cetirizine in reduction of adenoidal obstruction of the nasal airway. To examine the influence of these medicines on the adenoid hypertrophy (AH) we studied 43 children ages 4 to 9 years, who had AH and house dust mite allergy. Properly administered aqueous nasal fluticasone propionate and Cetirizine in standard doses can significantly reduce adenoidal hypertrophy and nasal airway obstructive symptoms in atopic children.
气道的变应性致敏发生在休克器官的黏膜或引流这些结构的淋巴站点。人类中最接近鼻黏膜的淋巴结构是腺样体。小儿腺样体阻塞鼻气道会导致显著的发病率,并且是常见的手术指征。由于缺乏有效的腺样体切除术替代药物,我们评估了标准剂量的局部鼻用丙酸氟替卡松和西替利嗪减轻鼻气道腺样体阻塞的效力。为了研究这些药物对腺样体肥大(AH)的影响,我们对43名4至9岁患有腺样体肥大和屋尘螨过敏的儿童进行了研究。标准剂量的鼻用丙酸氟替卡松水溶液和西替利嗪正确给药可显著减轻特应性儿童的腺样体肥大和鼻气道阻塞症状。