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慢性胰腺炎中的疼痛:通过治疗进行评估与缓解

Pain in chronic pancreatitis: assessment and relief through treatment.

作者信息

Seicean Andrada, Grigorescu Mircea, Tanţău Marcel, Dumitraşcu Dan L, Pop Diana, Mocan Teodora

机构信息

3rd Medical Clinic, "Iuliu Hatieganu" University of Medicine and Pharmacy, Str. Croitorilor no. 19-21, 400162 Cluj-Napoca, Romania.

出版信息

Rom J Gastroenterol. 2004 Mar;13(1):9-15.

Abstract

AIM

To assess two scores of pain used in chronic pancreatitis, to analyse the morphological factors identified by imaging techniques and the extrinsic factors involved in causing pain and in pain evolution during treatment.

PATIENTS AND METHODS

Pain was assessed by means of a unidimensional numeric scale and a multidimensional Mc Gill score in 50 patients with chronic pancreatitis. We prospectively followed up 28 patients over a period of 17 months.

RESULTS

Pain assessment by means of the two scores was statistically comparable. The multidimensional score correlated with the presence of Wirsung stenoses in the univariate analysis and with Wirsung stenoses and their diameter in the multivariate one. The smokers had a smaller rate of pain relief during the treatment. In cases with more morphological changes of severe chronic pancreatitis, pain relief was lower than in cases with fewer changes.

CONCLUSIONS

The McGill score is more appropriate for the quantitative assessment of pain. Smoking reduces the chances of pain relief under treatment. Duct stenoses and Wirsung diameter have the best correlation with pain intensity. The severe chronic pancreatitis changes are negative predictive factors for pain relief under treatment

摘要

目的

评估用于慢性胰腺炎的两种疼痛评分,分析影像学技术所识别的形态学因素以及治疗期间引起疼痛和疼痛演变的外在因素。

患者与方法

采用单维度数字评分法和多维度麦吉尔评分法对50例慢性胰腺炎患者的疼痛进行评估。我们对28例患者进行了为期17个月的前瞻性随访。

结果

两种评分方法对疼痛的评估在统计学上具有可比性。在单变量分析中,多维度评分与主胰管狭窄的存在相关,在多变量分析中与主胰管狭窄及其直径相关。吸烟者在治疗期间疼痛缓解率较低。在重度慢性胰腺炎形态学改变较多的病例中,疼痛缓解程度低于改变较少的病例。

结论

麦吉尔评分更适合用于疼痛的定量评估。吸烟会降低治疗期间疼痛缓解的几率。导管狭窄和主胰管直径与疼痛强度的相关性最佳。重度慢性胰腺炎改变是治疗期间疼痛缓解的负性预测因素。

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