Carey Michael P, Carey Kate B, Maisto Stephen A, Schroder Kerstin E E, Vanable Peter A, Gordon Christopher M
Center for Health and Behavior, Syracuse University, Syracuse, NY 13244, USA.
J Nerv Ment Dis. 2004 Apr;192(4):289-96. doi: 10.1097/01.nmd.0000120888.45094.38.
People living with a mental illness are disproportionately vulnerable to human immunodeficiency virus. The current study sought to examine the influence of psychiatric disorder, substance use disorder, and gender on risky sexual behavior in this vulnerable population. Participants were 228 female and 202 male outpatients (66% mood disorder, 34% schizophrenia), each of whom took part in a Structured Clinical Interview for the DSM-IV and a comprehensive assessment of sexual risk behavior. Univariate and multivariate analyses tested a priori hypotheses. The results indicated that risk behavior was more frequent among patients diagnosed with a mood disorder (compared with those diagnosed with schizophrenia) or a substance use disorder (compared with those without a comorbid disorder) or both. We recommend routine human immunodeficiency virus risk screening and risk reduction programs for this vulnerable population.
患有精神疾病的人群感染人类免疫缺陷病毒的风险格外高。本研究旨在探讨精神障碍、物质使用障碍及性别对这一脆弱人群危险性性行为的影响。研究对象为228名女性和202名男性门诊患者(66%为心境障碍,34%为精神分裂症),每位患者均接受了《精神疾病诊断与统计手册》第四版(DSM-IV)的结构化临床访谈以及性行为风险行为的全面评估。单因素和多因素分析对预先设定的假设进行了检验。结果表明,被诊断为心境障碍(与被诊断为精神分裂症的患者相比)或物质使用障碍(与无共病障碍的患者相比)或两者兼有的患者中,风险行为更为频繁。我们建议针对这一脆弱人群开展常规的人类免疫缺陷病毒风险筛查及风险降低项目。