Michaels E K, Pavel D G, Orellana P, Montes A, Olea E
Division of Urology, University of Illinois, Chicago.
J Urol. 1992 Sep;148(3 Pt 2):1015-21. doi: 10.1016/s0022-5347(17)36803-9.
Patients treated by extracorporeal shock wave lithotripsy (ESWL) are usually evaluated by excretory urography within 1 month after treatment to determine the clearance of stone debris and rule out asymptomatic obstruction. In an attempt to obtain more precise functional information, we used 99mtechnetium-diethylenetriaminepentaacetic acid and 131iodine-hippurate radionuclide renal imaging studies, and a plain abdominal radiograph as the initial followup study after ESWL of 64 kidneys in 55 patients. Of 53 kidneys studied within 60 days after ESWL 42 had abnormal radionuclide renal imaging studies demonstrating pelviocaliceal stasis, excretory delay or poor function, 8 of which required subsequent interventions for obstructing stone debris. Five patients had excretory delay after ESWL that was unexpected based on a pre-ESWL excretory urogram showing normal function without dilation. A subset of 23 patients with large stone burden or anatomical deformity from a prior operation had baseline radionuclide renal imaging studies before ESWL; function improved in 4 and worsened in 5 by radionuclide renal imaging studies after completion of treatment. A total of 19 patients had radionuclide renal imaging studies earlier (within 17 days) after ESWL because of poor function and/or large stone burden, and as expected they had evidence of obstruction from stone debris, which necessitated further followup. Our experience suggests that followup of ESWL by radionuclide renal imaging studies provides specific functional information that is of particular value in the management of patients with obstructing stone debris and/or diminished renal function. Radionuclide renal imaging studies may also reveal unsuspected obstruction or functional impairment after ESWL of uncomplicated stones, and is recommended as routine followup after ESWL.
接受体外冲击波碎石术(ESWL)治疗的患者通常在治疗后1个月内通过排泄性尿路造影进行评估,以确定结石碎片的清除情况并排除无症状性梗阻。为了获取更精确的功能信息,我们对55例患者的64个肾脏进行了ESWL治疗,并将锝-二乙三胺五乙酸和碘-131马尿酸盐放射性核素肾显像研究以及腹部平片作为初始随访检查。在ESWL后60天内对53个肾脏进行研究,其中42个肾脏的放射性核素肾显像研究异常,表现为肾盂肾盏淤滞、排泄延迟或功能不佳,其中8个需要后续干预以清除梗阻性结石碎片。5例患者在ESWL后出现排泄延迟,而ESWL前的排泄性尿路造影显示功能正常且无扩张,这一结果出乎意料。23例结石负荷大或既往手术导致解剖结构畸形的患者在ESWL前进行了基线放射性核素肾显像研究;治疗完成后,放射性核素肾显像研究显示4例功能改善,5例功能恶化。共有19例患者因功能不佳和/或结石负荷大在ESWL后更早(17天内)进行了放射性核素肾显像研究,正如预期的那样,他们有结石碎片梗阻的证据,这需要进一步随访。我们的经验表明,通过放射性核素肾显像研究对ESWL进行随访可提供特定的功能信息,这在处理梗阻性结石碎片和/或肾功能减退的患者时具有特殊价值。放射性核素肾显像研究还可能揭示单纯性结石ESWL后未被怀疑的梗阻或功能损害,建议将其作为ESWL后的常规随访检查。