Saunders Elijah
Division of Cardiology, University of Maryland School of Medicine, 419 West Redwood Street, Baltimore, MD 21201-1734, USA.
J Clin Hypertens (Greenwich). 2004 Apr;6(4 Suppl 1):19-25. doi: 10.1111/j.1524-6175.2004.03564.x.
Epidemiologic evidence indicates that African Americans are at greater risk for hypertension compared with other ethnic groups in the United States. The prevalence of hypertension is estimated to be approximately 37% for this group, compared with 20%-25% for non-Hispanic whites. Hypertension seems to follow a more malignant course in African Americans, possibly as a result of the higher prevalence of concomitant cardiovascular risk factors in this population. Compared with white persons with hypertension, these patients are at increased risk for left ventricular hypertrophy, heart failure, and end-stage renal disease. Data suggest that ethnicity may influence the response to certain types of antihypertensive medication. Additional data indicate that more aggressive use of combination therapy may improve clinical outcomes among high-risk hypertensive patients. Based on these findings, recommendations are made for the optimal clinical management of hypertension in African-American patients.
流行病学证据表明，与美国其他种族群体相比，非裔美国人患高血压的风险更高。据估计，该群体高血压患病率约为37%，而非西班牙裔白人的患病率为20%-25%。高血压在非裔美国人中似乎呈现出更恶性的病程，这可能是由于该人群中并发心血管危险因素的患病率较高。与患有高血压的白人相比，这些患者发生左心室肥厚、心力衰竭和终末期肾病的风险增加。数据表明，种族可能会影响对某些类型抗高血压药物的反应。更多数据表明，更积极地使用联合治疗可能会改善高危高血压患者的临床结局。基于这些发现，针对非裔美国高血压患者的最佳临床管理提出了建议。
