Yuyun Matthew F, Angwafo III Fru F, Koulla-Shiro Sinata, Zoung-Kanyi Jimmy
Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, UK.
Trop Med Int Health. 2004 Apr;9(4):520-5. doi: 10.1111/j.1365-3156.2004.01219.x.
To compare the prevalence of genitourinary abnormalities in men diagnosed with urinary tract infection (UTI) in a Cameroonian hospital and those without.
Consecutive adult men aged 18-75 years, whose midstream urine samples were received for microscopy, culture and sensitivity at the microbiology laboratory of the Yaounde University Teaching Hospital, Cameroon, constituted the study population. Genitourinary abnormalities were diagnosed from history, physical examination, abdominal and transrectal ultrasonography, plain abdominal X-ray, and if indicated urethrocystoscopy and biopsy.
Of the 206 patients who qualified, 179 completed the study and 63 (35.2%) were found to have UTI. A total of 41 (65.1%) patients with UTI (mean age 69.2 years) had at least one genitourinary abnormality, compared to 13 (11.2%) of those without UTI (mean age 61.9 years) (P < 0.001). The age-adjusted prevalence of genitourinary abnormalities was 59.4% in the UTI group and 12.1% in the non-UTI group (P < 0.001). The most frequent genitourinary abnormality in men with UTI was benign prostatic enlargement, followed by urethral stricture. The crude odds ratio (95% confidence intervals) for UTI associated with genitourinary abnormality was 14.77 (6.80-32.05), and the adjusted odds ratio 11.51 (7.08-29.46).
Urological evaluation of Cameroonian men with UTI, using simple history taking, physical examination, ultrasound examination and plain abdominal X-ray, could have significant clinical benefits in this tropical African region.
比较喀麦隆一家医院中被诊断患有尿路感染（UTI）的男性与未患尿路感染的男性泌尿生殖系统异常的患病率。
连续纳入年龄在18 - 75岁的成年男性，其在喀麦隆雅温得大学教学医院微生物实验室接受了用于显微镜检查、培养及药敏试验的中段尿样本，构成研究人群。通过病史、体格检查、腹部及经直肠超声检查、腹部平片，必要时进行尿道膀胱镜检查及活检来诊断泌尿生殖系统异常。
在符合条件的206例患者中，179例完成了研究，其中63例（35.2%）被发现患有UTI。共有41例（65.1%）患有UTI的患者（平均年龄69.2岁）至少有一项泌尿生殖系统异常，而未患UTI的患者中有13例（11.2%）（平均年龄61.9岁）出现此类情况（P < 0.001）。UTI组经年龄调整后的泌尿生殖系统异常患病率为59.4%，非UTI组为12.1%（P < 0.001）。患有UTI的男性中最常见的泌尿生殖系统异常是良性前列腺增生，其次是尿道狭窄。与泌尿生殖系统异常相关的UTI的粗比值比（95%置信区间）为14.77（6.80 - 32.05），调整后的比值比为11.51（7.08 - 29.46）。
在这个热带非洲地区对喀麦隆患有UTI的男性进行泌尿外科评估，采用简单的病史采集、体格检查、超声检查及腹部平片，可能会带来显著的临床益处。
