人格障碍和社交焦虑预示着惊恐障碍药物及行为治疗的反应延迟。
Personality disorder and social anxiety predict delayed response in drug and behavioral treatment of panic disorder.
作者信息
Berger Peter, Sachs Gabriele, Amering Michaela, Holzinger Anita, Bankier Bettina, Katschnig Heinz
机构信息
Department of Psychiatry, Division of Social Psychiatry, University of Vienna, Austria.
出版信息
J Affect Disord. 2004 May;80(1):75-8. doi: 10.1016/S0165-0327(03)00043-0.
BACKGROUND
The aim of this study was to analyze the impact of pretreatment characteristics and personality disorders on the onset of response in the treatment of panic disorder.
METHODS
The data of 73 out-patients with panic disorder who had completed at least 6 weeks of a randomized trial of 24 weeks of either paroxetine only or paroxetine combined with cognitive group-therapy were analyzed in a Cox proportional hazards model.
RESULTS
The likelihood of having responded to treatment (defined by a CGI rating of improvement) was more than twice as high for patients without a personality disorder or social phobia than for Patients with a personality disorder or social phobia.
CONCLUSIONS
We suggest that patients with these characteristics do benefit from prolonged treatment, and they may profit from an additional treatment focused on social anxiety.
背景
本研究旨在分析惊恐障碍治疗中预处理特征和人格障碍对反应 onset 的影响。
方法
在Cox比例风险模型中分析了73例完成至少6周随机试验（仅帕罗西汀或帕罗西汀联合认知团体治疗，为期24周）的惊恐障碍门诊患者的数据。
结果
没有人格障碍或社交恐惧症的患者对治疗有反应（由CGI改善评分定义）的可能性是有人格障碍或社交恐惧症患者的两倍多。
结论
我们建议具有这些特征的患者确实能从延长治疗中获益，并且他们可能从专注于社交焦虑的额外治疗中受益。
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