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牙齿疾病与颌骨的放射性核素成像

Dental diseases and radionuclide imaging of the jaws.

作者信息

Arias Jose A, Pardo Carlos, Olmos Antonio, Cuadrado Maria L, Ruibal Alvaro

机构信息

Faculty of Health Sciences, Alfonso X el Sabio University, Villanueva de la Canada, Madrid, Spain.

出版信息

Nucl Med Commun. 2004 Mar;25(3):305-10. doi: 10.1097/00006231-200403000-00015.

Abstract

The aim of this study was to compare the results of radionuclide bone scans of the jaws with data obtained at the nuclear medicine department from a brief and feasible dental history, taking special account of cases with a positive scan and no recent dental events. Ninety-eight patients undergoing radionuclide bone scan as part of their diagnosis in non-dental, oncological and non-oncological diseases were imaged with 99mTc-labelled oxidronate. Superior and inferior halves of the mandible and maxilla (392 quadrants) were regarded as normal or having an abnormally high uptake. A recent (1 year) dental history was also obtained through a brief questionnaire and data were referred to each quadrant of the jaws. The association between the bone scan and dental disease was assessed by means of the chi-squared test. The overall results of scintigraphy and history coincided in 66 patients (46 with abnormal and 20 with normal findings; P = 0.002). Twenty-five patients had a positive scintigram without any known dental disorder. Results of scintigraphy and history coincided in 254 quadrants (78 with abnormal and 176 with normal findings; P < 0.001). Eighty-three quadrants had hot spots in the scintigram without any known dental lesion. It can be concluded that abnormal jaw scintigrams are frequent in patients without known dental disease, and this may indicate silent osteoblastic activity. These observations should be reported to the dentist for several reasons. First, they may reveal asymptomatic dental lesions. Second, the use of oral prostheses and implants is increasing and they require the support of healthy alveolar bone.

摘要

本研究的目的是将颌骨放射性核素骨扫描结果与核医学科通过简短且可行的牙科病史获得的数据进行比较,特别关注扫描结果为阳性且近期无牙科事件的病例。98例因非牙科、肿瘤及非肿瘤疾病诊断而接受放射性核素骨扫描的患者用99mTc标记的奥曲膦进行成像。将下颌骨和上颌骨的上半部分和下半部分(共392个象限)视为正常或摄取异常增高。还通过简短问卷获取了近期(1年)的牙科病史,并将数据对应到颌骨的每个象限。采用卡方检验评估骨扫描与牙科疾病之间的关联。骨扫描和病史的总体结果在66例患者中相符(46例结果异常,20例结果正常;P = 0.002)。25例患者骨扫描呈阳性,但无任何已知的牙科疾病。骨扫描和病史结果在254个象限中相符(78个象限结果异常,176个象限结果正常;P < 0.001)。83个象限在骨扫描中有热点,但无任何已知的牙病变。可以得出结论,在无已知牙科疾病的患者中,颌骨扫描异常很常见,这可能表明存在无症状的成骨细胞活动。出于几个原因,这些观察结果应报告给牙医。首先,它们可能揭示无症状的牙病变。其次,口腔假体和植入物的使用正在增加,它们需要健康牙槽骨的支持。

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