Kostović Kresimir, Pasić Aida
Department of Dermatology and Venerology, Zagreb University Hospital Center, Croatia.
Acta Dermatovenerol Croat. 2004;12(1):42-50.
Along with topical and systemic therapy, phototherapy is one of the three fundamental treatment options for managing psoriasis. The use of UVB continues to be one of the most important therapeutic interventions for mild to moderate psoriasis. An advance in UVB phototherapy has been the introduction of narrowband UVB lamps (311 nm). UVB lamps are superior to conventional broadband UVB in clearing psoriasis. PUVA is very effective therapy and is still the most effective form of phototherapy for severe, extensive form od the disease. There has been a trend towards whole-body PUVA-bath. Advantages of PUVA bath are lack of gastrointestinal side effects and no need for post-treatment eye photoprotection because there is no systemic photosensitization. UVB and PUVA can be administered in combination with a variety of topical and systemic treatments to achieve more effective results more quickly. The most recent form of phototherapy, 308-nm excimer laser, holds promise for becoming a useful tool in the treatment of stable, localized psoriasis.
除局部和全身治疗外,光疗是治疗银屑病的三种基本治疗选择之一。UVB的使用仍然是治疗轻至中度银屑病最重要的治疗干预措施之一。UVB光疗的一项进展是引入了窄带UVB灯(311nm)。UVB灯在清除银屑病方面优于传统的宽带UVB。补骨脂素加紫外线A(PUVA)是非常有效的治疗方法,仍然是治疗严重、广泛型疾病最有效的光疗形式。全身PUVA浴有增加的趋势。PUVA浴的优点是没有胃肠道副作用,且由于没有全身光敏作用,治疗后无需眼部光防护。UVB和PUVA可与多种局部和全身治疗联合使用,以更快地获得更有效的结果。最新的光疗形式,308nm准分子激光,有望成为治疗稳定、局限性银屑病的有用工具。