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我们处理大型前庭神经鞘瘤的手术经验。

Our surgical experience with large vestibular schwannomas.

作者信息

Skrivan J, Zvĕrina E, Betka J, Kluh J, Kraus J

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Institute of Postgradual Education, Faculty Hospital Motol, V Uvalu 84, 150 06-Praha 5 Czech Republic.

出版信息

Otolaryngol Pol. 2004;58(1):69-72.

Abstract

Our aim is to remove large vestibular schwannomas (VS) radically with minimal morbidity. Usually, these tumours cannot not be treated by irradiation. In the years 1997-2003, 69 VS were operated in the Department of Otorhinolaryngology, Head and Neck Surgery of the First Medical Faculty in Prague, Czech Republic. Prevailing majority of these tumours were of the 4th grade (House classification), compressing the brainstem. Six patients in the group suffered from neurofibromatosis 2, in five cases the patients were indicated for neurosurgery due to rapid tumour growth after previous irradiation. All tumours were radically removed using a retromastoid osteoplastic and translab approach with an intraoperative nerve monitoring. Good function of the facial nerve was achieved in 90%. The nerve had to be resutured in 4 cases with consequent satisfactory results, cross anatomosis was not performed. Hearing function was preserved in 8% of patients only. In 6 patients with neurofibromatosis 2, the auditory brainstem implant (ABI) was used to preserve hearing. This study demonstrates that a radical removal of large vestibular schwannomas is possible using a minimally invasive surgical technique and peroperative nerve monitoring with a good impact on quality of life. Auditory brainstem implants bring a new chance of hearing after tumour removal in patients with NF2.

摘要

我们的目标是以最低的发病率彻底切除大型前庭神经鞘瘤(VS)。通常,这些肿瘤无法通过放疗进行治疗。1997年至2003年期间,捷克共和国布拉格第一医学院耳鼻咽喉头颈外科对69例VS进行了手术。这些肿瘤绝大多数属于4级(House分类),压迫脑干。该组中有6例患者患有神经纤维瘤病2型,5例患者因先前放疗后肿瘤快速生长而被转诊至神经外科。所有肿瘤均采用乳突后骨成形和经迷路入路并术中进行神经监测的方法彻底切除。90%的患者面神经功能良好。4例患者面神经需要重新缝合,结果令人满意,未进行交叉吻合术。仅8%的患者听力功能得以保留。6例神经纤维瘤病2型患者使用了听觉脑干植入物(ABI)来保留听力。本研究表明,使用微创外科技术和术中神经监测有可能彻底切除大型前庭神经鞘瘤,对生活质量有良好影响。听觉脑干植入物为NF2患者肿瘤切除后带来了新的听力机会。

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