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在一个经过挑选的大型高血压人群中进行家庭血压测量及其与血压控制的关系。

Home blood pressure measurement and its relationship with blood pressure control in a large selected hypertensive population.

作者信息

Cuspidi C, Meani S, Fusi V, Salerno M, Valerio C, Severgnini B, Catini E, Leonetti G, Magrini F, Zanchetti A

机构信息

Istituto di Medicina Cardiovascolare and Centro Interuniversitario di Fisiologia Clinica e Ipertensione,Università di Milano, Milano, Italy.

出版信息

J Hum Hypertens. 2004 Oct;18(10):725-31. doi: 10.1038/sj.jhh.1001737.

Abstract

Despite the impressive increase of home blood pressure monitoring (BPM) among hypertensive patients over the last few years, a limited number of studies have analysed the rate of home BPM and its relationship with target blood pressure (BP) control, in representative samples of the hypertensive population. The objectives of the study were first to evaluate the prevalence of home BPM in a large selected group of treated hypertensive patients referred to our outpatient hypertension hospital clinic. Second, to assess the rate of satisfactory clinic BP control in patients with or without familiarity with home BPM. In all, 1350 consecutive hypertensive patients who attended our hypertension centre during a period of 12 months and were regularly followed up by the same medical team were included in the study. After informed consent all patients underwent the following procedures: (1) accurate medical history (implemented by a structured questionnaire on demographic and clinical characteristics, including questions concerning home BPM); (2) physical examination; (3) clinic BP measurement; (4) routine examinations; and (5) standard 12-lead electrocardiogram. A total of 897 patients (66%) out of 1350 (687 men, 663 women, age 58.6 +/- 12.3 years, mean clinic BP 141 +/- 16/87 +/- 9 mmHg ) were regularly practising home BPM. In this group of patients, home BPM was associated with a significantly greater rate of satisfactory BP control (49.2 vs 45.6%, P < 0.01). Patients performing home BPM were more frequently men (54 vs 46%, P < 0.02 ) younger (average age 57.8 +/- 12.0 vs 60.3 +/- 12.7 years, P < 0.001) and with a higher educational level (defined by more than 8 years of school, 71 vs 55%, P < 0.05) than their counterparts. There were no significant differences in duration of hypertension, hypercholesterolaemia, obesity, smoking, diabetes, associated cardiovascular diseases, left ventricular hypertrophy and compliance with drug treatment. This study demonstrates that: (1) home BPM is widely performed by hypertensive patients managed in a hypertension hospital clinic; (2) this practice is associated with a significantly higher rate of clinic BP control; and (3) age, male gender and educational level influence the adoption of home BPM.

摘要

尽管在过去几年中高血压患者的家庭血压监测(BPM)显著增加,但在高血压人群的代表性样本中,仅有有限的研究分析了家庭BPM的使用率及其与血压控制目标的关系。本研究的目的,首先是评估在我院门诊高血压诊疗中心接受治疗的大量高血压患者中家庭BPM的普及率。其次,评估熟悉或不熟悉家庭BPM的患者的诊室血压控制达标率。本研究共纳入了1350例连续就诊于我院高血压中心、并由同一医疗团队定期随访的高血压患者。在获得知情同意后,所有患者均接受了以下检查:(1)详细的病史采集(通过一份关于人口统计学和临床特征的结构化问卷进行,包括有关家庭BPM的问题);(2)体格检查;(3)诊室血压测量;(4)常规检查;以及(5)标准12导联心电图检查。1350例患者(687例男性,663例女性,年龄58.6±12.3岁,平均诊室血压141±16/87±9 mmHg)中,共有897例(66%)患者经常进行家庭BPM。在这组患者中,家庭BPM与显著更高的血压控制达标率相关(49.2%对45.6%,P<0.01)。进行家庭BPM的患者中男性比例更高(54%对46%,P<0.02),年龄更小(平均年龄57.8±12.0岁对(60.3\pm12.7)岁,P<0.001),且教育水平更高(定义为接受过8年以上学校教育,71%对55%,P<0.05)。在高血压病程、高胆固醇血症、肥胖、吸烟、糖尿病、相关心血管疾病、左心室肥厚以及药物治疗依从性方面,两组之间无显著差异。本研究表明:(1)在高血压医院门诊接受治疗的高血压患者中,家庭BPM的应用较为广泛;(2)这种做法与显著更高的诊室血压控制达标率相关;以及(3)年龄、性别和教育水平会影响家庭BPM的采用情况。

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