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颅外和颅内椎动脉狭窄的血管成形术或支架置入术。

Angioplasty or stenting of extra- and intracranial vertebral artery stenoses.

作者信息

Hauth Elke A M, Gissler H Martin, Drescher Robert, Jansen Christian, Jaeger Horst J, Mathias Klaus D

机构信息

Department of Radiology and Interventional Radiology, University Hospital Essen, Essen, Germany.

出版信息

Cardiovasc Intervent Radiol. 2004 Jan-Feb;27(1):51-7. doi: 10.1007/s00270-003-0028-7.

Abstract

PURPOSE

To determine the feasibility and safety of angioplasty or angioplasty and stenting of extra- and intracranial vertebral artery (VA) stenosis.

METHODS

In 16 consecutive patients (9 men, 7 women; mean age 61 years, range 49-74 years) 16 stenotic VAs were treated with angioplasty or angioplasty and stenting. Eleven stenoses were localized in V1 segment, 1 stenosis in V2 segment and 4 stenoses in V4 segment of VA. Fourteen VA stenoses were symptomatic, 2 asymptomatic. The etiology of the stenoses was atherosclerotic in all cases.

RESULTS

Angioplasty was performed in 8 of 11 V1 and 2 of 4 V4 segments of the VA. In 3 of 11 V1 segments and 2 of 4 V4 segments of the VA we combined angioplasty with stenting. The procedures were successfully performed in 14 of 16 VAs (87%). Complications were asymptomatic vessel dissection resulting in vessel occlusion in 1 of 11 V1 segments and asymptomatic vessel dissection in 2 of 4 V4 segments of the VA. One patient died in the 24-hr period after the procedure because of subarachnoid hemorrhage as a complication following vessel perforation of the treated V4 segment.

CONCLUSION

Angioplasty or angioplasty and stenting of extracranial VA stenoses can be performed with a high technical success rate and a low complication rate. In intracranial VA stenosis the procedure is technically feasible but complications can be life-threatening. The durability and procedural complication rates of primary stenting without using predilation in extra- and intracranial VA stenosis should be defined in the future.

摘要

目的

确定对颅外和颅内椎动脉(VA)狭窄进行血管成形术或血管成形术加支架置入术的可行性和安全性。

方法

连续16例患者(9例男性,7例女性;平均年龄61岁,范围49 - 74岁),对16条狭窄的椎动脉进行血管成形术或血管成形术加支架置入术。11条狭窄位于椎动脉V1段,1条位于V2段,4条位于V4段。14条椎动脉狭窄有症状,2条无症状。所有病例狭窄的病因均为动脉粥样硬化。

结果

在椎动脉的11个V1段中的8个以及4个V4段中的2个进行了血管成形术。在椎动脉的11个V1段中的3个以及4个V4段中的2个,我们将血管成形术与支架置入术相结合。16条椎动脉中的14条(87%)手术成功完成。并发症包括11个V1段中的1个出现无症状血管夹层导致血管闭塞,以及4个V4段中的2个出现无症状血管夹层。1例患者在术后24小时内死亡,原因是治疗的V4段血管穿孔后并发蛛网膜下腔出血。

结论

颅外椎动脉狭窄的血管成形术或血管成形术加支架置入术技术成功率高且并发症发生率低。颅内椎动脉狭窄的手术在技术上是可行的,但并发症可能危及生命。未来应明确在颅外和颅内椎动脉狭窄中不进行预扩张的原发性支架置入术的耐久性和手术并发症发生率。

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