Banegas José R, Segura Julián, Ruilope Luis M, Luque Manuel, García-Robles Rafael, Campo Carlos, Rodríguez-Artalejo Fernando, Tamargo Juan
Department of Preventive Medicine and Public Health, of Medicine, Universidad Autónoma de Madrid, Spain.
Hypertension. 2004 Jun;43(6):1338-44. doi: 10.1161/01.HYP.0000127424.59774.84. Epub 2004 Apr 26.
Goal blood pressure (BP) was defined by the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-VI) and the World Health Organization-International Society of Hypertension (WHO/ISH) as <140 mm Hg systolic and <90 mm Hg diastolic for the general and <130 mm Hg systolic and <85 mm Hg diastolic for special high-risk populations. However, there are few reports that address BP control among special subgroups of hypertensives by reference to targeted BP. We therefore conducted a study to evaluate BP control of 4049 hypertensives in 47 hospital-based hypertension units in Spain. Overall, 42% of patients achieved goal BP (<140 mm Hg systolic and <90 mm Hg diastolic). Only 13% of diabetic patients and 17% of those with renal disease achieved the BP goal (<130 mm Hg systolic and <85 mm Hg diastolic), and only 10% and 12%, respectively, achieved the even more rigorous goal (<130 mm Hg systolic and <80 mm Hg diastolic). Likewise, only 18% of patients in JNC-VI risk group C and 17% of WHO/ISH high-risk patients attained a goal BP <130 mm Hg systolic and <85 mm Hg diastolic. BP control (<125 mm Hg systolic and <75 mm Hg diastolic) was extremely low (2%) in patients with proteinuria >1 g/d. Poorer BP control was observed among patients at high risk, with diabetes, renal disease, or obesity, than in lower-risk groups. BP control was lower for systolic than for diastolic BP. In >50% of uncontrolled patients, no measures were taken by doctors to optimize pharmacologic treatment, and approximately one-third of patients were still using drug monotherapy. Control of BP, particularly of systolic BP, is still far from optimal in hospital-based hypertension units. Patients at high risk, with diabetes or proteinuria, warrant focused attention. Moreover, a more aggressive behavior of doctors treating uncontrolled hypertension is needed.
美国国家联合委员会关于高血压预防、检测、评估及治疗的第六次报告(JNC-VI)以及世界卫生组织-国际高血压学会(WHO/ISH)将目标血压定义为:一般人群收缩压<140 mmHg且舒张压<90 mmHg,特殊高危人群收缩压<130 mmHg且舒张压<85 mmHg。然而,很少有报告提及按照目标血压对高血压特殊亚组人群的血压控制情况。因此,我们开展了一项研究,以评估西班牙47个医院高血压科室中4049例高血压患者的血压控制情况。总体而言,42%的患者达到了目标血压(收缩压<140 mmHg且舒张压<90 mmHg)。仅有13%的糖尿病患者和17%的肾病患者达到了血压目标(收缩压<130 mmHg且舒张压<85 mmHg),分别仅有10%和12%的患者达到了更为严格的目标(收缩压<130 mmHg且舒张压<80 mmHg)。同样,JNC-VI风险组C中仅有18%的患者以及WHO/ISH高危患者中仅有17%的患者达到了收缩压<130 mmHg且舒张压<85 mmHg的目标血压。蛋白尿>1 g/d的患者血压控制在<125 mmHg收缩压且<75 mmHg舒张压的水平极低(2%)。与低风险组相比,高危患者、糖尿病患者、肾病患者或肥胖患者的血压控制情况较差。收缩压的控制情况低于舒张压。在超过50%未达标的患者中,医生未采取措施优化药物治疗,约三分之一的患者仍在使用单一药物治疗。在医院高血压科室中,血压控制,尤其是收缩压控制,仍远未达到最佳状态。高危患者、糖尿病患者或蛋白尿患者需要重点关注。此外,治疗未达标的高血压患者时,医生需要采取更积极的措施。