Enríquez R, Cabezuelo J B, Escolano C, Pérez M, Amorós F, Gutiérrez-Rodero F, Reyes A
Nephrology Section, General Hospital of Elche, Spain.
Clin Nephrol. 2004 Apr;61(4):278-81. doi: 10.5414/cnp61278.
Postinfectious proliferative glomerulonephritis may occur in HIV-infected patients, although it is not a common cause of severe acute renal failure in them. We report a woman with HIV infection, who developed hypocomplementemic acute nephritic syndrome 10 days after an upper respiratory infection. Systemic diseases were excluded. The serum creatinine level increased to 6.6 mg/dl. Renal biopsy showed diffuse endocapillary proliferative glomerulonephritis, with mesangial and capillary walls, granular deposits of IgG and C3 by immunofluorescence. She was given corticosteroids with progressive normalization of her renal function. No opportunistic infections have occurred during 1-year follow-up.
感染后增殖性肾小球肾炎可发生于HIV感染患者,尽管它并非此类患者严重急性肾衰竭的常见病因。我们报告一名HIV感染女性,她在上呼吸道感染10天后出现低补体血症性急性肾炎综合征。排除了全身性疾病。血清肌酐水平升至6.6mg/dl。肾活检显示弥漫性毛细血管内增生性肾小球肾炎,免疫荧光显示系膜和毛细血管壁有IgG和C3颗粒状沉积。给予她糖皮质激素治疗后肾功能逐渐恢复正常。在1年的随访期间未发生机会性感染。