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儿童行为问题和家庭功能对经济弱势1型糖尿病患儿治疗依从性和血糖控制的预测作用:一项前瞻性研究

Child behavior problems and family functioning as predictors of adherence and glycemic control in economically disadvantaged children with type 1 diabetes: a prospective study.

作者信息

Cohen Dana M, Lumley Mark A, Naar-King Sylvie, Partridge Ty, Cakan Nedim

机构信息

Wayne State University, Detroit, Michigan 48202, USA.

出版信息

J Pediatr Psychol. 2004 Apr-May;29(3):171-84. doi: 10.1093/jpepsy/jsh019.

Abstract

OBJECTIVE

This prospective study examined how child behavior problems and family functioning predict adherence behavior and glucose regulation (glycemic control) in a sample of economically disadvantaged children.

METHODS

Children with type 1 diabetes (N = 116; 58.6% African American) were assessed for externalizing and internalizing behavior problems and family adaptability and cohesion and followed for a mean of 3.8 years. Glycemic control (glycosylated hemoglobin [HbA1c]) was assessed at baseline and follow-up, and adherence was assessed at follow-up.

RESULTS

Analyses controlled for baseline HbA1c and years to follow-up. Multivariate analyses indicated that better adherence was predicted by high family cohesion. Better glycemic control was predicted by high family cohesion, the absence of externalizing behavior problems, and the presence of internalizing behavior problems. In addition, tests of moderation indicated that better follow-up glycemic control occurred among girls from high cohesion families and younger children from low adaptability families. Although better adherence predicted better glycemic control, adherence did not mediate the relationships of behavior problems or family functioning with glycemic control.

CONCLUSIONS

A child's behavior problems and family functioning may influence both adherence to the diabetes regimen and glycemic control several years later, suggesting the potential value of interventions that address child behavior and family functioning.

摘要

目的

本前瞻性研究探讨了在经济条件不利的儿童样本中,儿童行为问题和家庭功能如何预测依从行为和血糖调节(血糖控制)。

方法

对116名1型糖尿病儿童(非裔美国人占58.6%)进行外化和内化行为问题以及家庭适应性和凝聚力评估,并随访平均3.8年。在基线和随访时评估血糖控制(糖化血红蛋白[HbA1c]),在随访时评估依从性。

结果

分析对基线HbA1c和随访年限进行了控制。多变量分析表明,高家庭凝聚力可预测更好的依从性。高家庭凝聚力、不存在外化行为问题以及存在内化行为问题可预测更好的血糖控制。此外,调节检验表明,在高凝聚力家庭的女孩和低适应性家庭的年幼儿童中,随访时血糖控制更好。虽然更好的依从性可预测更好的血糖控制,但依从性并未介导行为问题或家庭功能与血糖控制之间的关系。

结论

儿童的行为问题和家庭功能可能会影响数年后对糖尿病治疗方案的依从性和血糖控制,这表明解决儿童行为和家庭功能问题的干预措施具有潜在价值。

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