Synthesis of cyclic beta-amino acid esters from methionine, allylglycine, and serine.
作者信息
Gardiner James, Anderson Kelly H, Downard Alison, Abell Andrew D
机构信息
Department of Chemistry, University of Canterbury, Christchurch, New Zealand.
出版信息
J Org Chem. 2004 May 14;69(10):3375-82. doi: 10.1021/jo049794g.
PMID:15132545
Abstract
Here we report a versatile ring-closing metathesis-based approach to 5-, 6-, and 7-membered cyclic beta-amino esters starting with simple and readily available building blocks-methionine, allylglycine, and serine-where the nature of the amino acid determines the size of the carbocyclic ring.
摘要
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