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[传染性单核细胞增多症所致自发性脾破裂:病例报告]

[Spontaneous splenic rupture due to infectious acute mononucleosis: case report].

作者信息

Greco L, De Gennaro E, Degara A, Papa U

机构信息

U.O. Chirurgia Generale, Ospedale di Tione di Trento.

出版信息

Ann Ital Chir. 2003 Sep-Oct;74(5):589-91.

Abstract

Infectious mononucleosis is an acute, viral, illness associated with a high incidence of splenomegaly. Spontaneous splenic rupture is a rare but life-threatening complication of infectious mononucleosis. The authors report the case of a 19-year-old patient with an infectious mononucleosis causing a spontaneous splenic rupture. When rupture occurs the mortality has been significant. The spleen may be vulnerable for the histopathologic changes that occur as a result of this illness. Two thirds of patients with infectious mononucleosis develop an enlarged spleen, but in only 0.5% of all patients will it rupture. Abdominal pain and tachycardia are unusual in uncomplicated infectious mononucleosis and should alert a doctor to the possibility of spontaneous splenic rupture. The diagnosis of splenic rupture may be confirmed in a variety of ways. In this patient ultrasound and Rutkow's criteria may aid in establishing the diagnosis. In patients with infectious mononucleosis suspected of having rupture of the spleen, a rapid but thorough assessment and prompt implementation of appropriate management should minimize the associated morbidity and mortality. On the basis of review of the medical literature and of our own experience, we advocate emergent splenectomy for spontaneous splenic rupture in patients with infectious mononucleosis.

摘要

传染性单核细胞增多症是一种急性病毒性疾病,脾肿大发生率较高。自发性脾破裂是传染性单核细胞增多症罕见但危及生命的并发症。作者报告了一例19岁因传染性单核细胞增多症导致自发性脾破裂的患者。脾破裂发生时死亡率较高。由于这种疾病,脾脏可能因组织病理学变化而变得脆弱。三分之二的传染性单核细胞增多症患者会出现脾脏肿大,但在所有患者中只有0.5%的脾脏会破裂。腹痛和心动过速在无并发症的传染性单核细胞增多症中不常见,应提醒医生注意自发性脾破裂的可能性。脾破裂的诊断可以通过多种方式得到证实。在该患者中,超声检查和鲁特科夫标准可能有助于确诊。对于怀疑有脾脏破裂的传染性单核细胞增多症患者,快速而全面的评估以及及时实施适当的治疗应能将相关的发病率和死亡率降至最低。基于对医学文献和我们自身经验的回顾,我们主张对传染性单核细胞增多症导致自发性脾破裂的患者进行急诊脾切除术。

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