Nottebohm Fernando
Lab Anim (NY). 2004 May;33(5):23-5. doi: 10.1038/laban0504-23.
During the last 30 years, a number of revolutionary discoveries in the field of neuroscience have come from what was, at first, an unexpected direction: songbird research. Investigations into seasonal and sex-specific differences in birdsong development have led to important revelations about the impact of sex hormones on brain development and the hormonally controlled plasticity of brain structure, as well as the particularly surprising discovery that neurogenesis continues to occur in the adult brain (see Harding, p. 28). The work of Fernando Nottebohm is widely recognized as having played a key role in bringing these findings to light and thus forcing a general re-examination of established principles of neuroscience. Fernando Nottebohm is Dorothea L. Leonhardt Distinguished Professor at The Rockefeller University, and Director of The Rockefeller Field Research Center for Ethology and Ecology, a 1,200-acre facility located in Millbrook, NY, that provides researchers the opportunity to study behavior and brain function under natural conditions. Nottebohm's pioneering work on the neural control of birdsong has led to major discoveries with large impacts in the fields of animal behavior and neuroscience, and has made him one of the founders of neuroethology, the study of how the nervous system controls animal behavior. Nottebohm is a Member of the National Academy of Sciences, USA, and a Fellow of the American Association for the Advancement of Science and of the American Academy of Arts and Sciences. We had a chance to sit down with him to discuss his distinguished career working with laboratory birds.
在过去30年里,神经科学领域的一些革命性发现来自一个起初意想不到的方向:鸣禽研究。对鸟鸣发育过程中季节性和性别特异性差异的研究,揭示了性激素对大脑发育的影响、大脑结构的激素控制可塑性,以及一个特别令人惊讶的发现,即成年大脑中仍会发生神经发生(见哈丁,第28页)。费尔南多·诺特博姆的工作在揭示这些发现并促使人们对神经科学的既定原则进行全面重新审视方面发挥了关键作用,这一点得到了广泛认可。费尔南多·诺特博姆是洛克菲勒大学的多萝西娅·L·莱昂哈特杰出教授,也是洛克菲勒动物行为学与生态学野外研究中心主任。该研究中心位于纽约米尔布鲁克,占地1200英亩,为研究人员提供了在自然条件下研究行为和大脑功能的机会。诺特博姆在鸟鸣神经控制方面的开创性工作,在动物行为和神经科学领域取得了重大发现,产生了深远影响,使他成为神经行为学(研究神经系统如何控制动物行为的学科)的创始人之一。诺特博姆是美国国家科学院院士,也是美国科学促进会以及美国艺术与科学院的院士。我们有幸与他坐下来,讨论他与实验鸟类相关的杰出职业生涯。