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[体外冲击波治疗含钙胆囊结石]

[Extracorporeal shock wave treatment of calcium containing gallbladder calculi].

作者信息

Meiser G, Lexer G, Heinerman M, Zukriegel M, Kaindl H, Pimpl W, Waclawiczek H W, Sungler P, Schneeberger V, Boeckl O

机构信息

I. Chirurgische Abteilung, Landeskrankenanstalten Salzburg.

出版信息

Wien Klin Wochenschr. 1992;104(15):451-5.

PMID:1514291
Abstract

A total of 50 patients--37 female and 13 male--with an average age of 50 +/- 27 years (23-86 years), suffering from rim-calcified gallbladder stones, underwent extracorporeal shock-wave lithotripsy (ESWL), using an ultrasound-guided overhead module of Lithostar Plus (Siemens Company). The total number of stones was 87, with an average diameter of 16 +/- 7 (7-38) mm. 29 patients had a solitary stone, 13 had two and 8 patients three or more stones. All patients received adjunct medication of 10 mg/kg body weight chenodeoxycholic and ursodeoxycholic acid 14 days prior to ESWL as a single bedtime dose. An average number of 5,300 +/- 2,200 shock waves (1,200-15,000) was applied for stone disintegration. The corresponding energy amounted to 750 bar. 29 patients needed one, 21 two or more treatments. After ESWL a variety of clinical abnormalities was observed: flank pain (15%), transient microhaematuria (33%) and transient macrohaematuria (2%). Subsequent to ESWL 5 patients suffered from complications such as biliary obstruction 3 weeks to 9 months after treatment and had to undergo ERCP. Three times endoscopic papillotomy was performed to remove stones from the common bile duct. Up to now 4 patients have undergone cholecystectomy: acute cholecystitis (n = 3), recurrent colicky pain (n = 1). 20 patients have been followed up over a 12-month period; 12 of them are completely free of stones and fragments.

摘要

共有50例患者——37例女性和13例男性——平均年龄为50±27岁(23 - 86岁),患有边缘钙化胆囊结石,使用Lithostar Plus(西门子公司)的超声引导头顶模块进行了体外冲击波碎石术(ESWL)。结石总数为87枚,平均直径为16±7(7 - 38)毫米。29例患者有单个结石,13例有两个结石,8例有三个或更多结石。所有患者在ESWL前14天接受了辅助药物治疗,即每晚睡前单次服用10毫克/千克体重的鹅去氧胆酸和熊去氧胆酸。平均施加了5300±2200次冲击波(1200 - 15000次)用于结石破碎。相应能量为750巴。29例患者需要进行一次治疗,21例需要两次或更多次治疗。ESWL后观察到多种临床异常情况:胁腹疼痛(15%)、短暂性镜下血尿(33%)和短暂性肉眼血尿(2%)。ESWL后,5例患者出现并发症,如治疗后3周至9个月出现胆道梗阻,不得不接受内镜逆行胰胆管造影术(ERCP)。进行了三次内镜乳头切开术以清除胆总管结石。到目前为止,4例患者接受了胆囊切除术:急性胆囊炎(n = 3),复发性绞痛(n = 1)。20例患者接受了为期12个月的随访;其中12例完全没有结石和碎片。

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