Hussein J, Fortney J A
Dugald Baird Centre for Research on Women's Health, Department of Obstetrics and Gynaecology, University of Aberdeen, Aberdeen Maternity Hospital, Scotland, UK.
Int J Gynaecol Obstet. 2004 Jun;85 Suppl 1:S52-61. doi: 10.1016/j.ijgo.2004.01.010.
To identify new and underutilized technologies to reduce maternal mortality related to puerperal sepsis in developing countries.
Review of current medical literature.
The literature indicates that infection-control protocols and evidence-based procedures--including prophylactic antibiotics for cesarean section or preterm rupture of membranes, and updated antibiotic regimens--should be widely adopted. Devices such as hand rubs, needle-disposal systems, and rapid microbiological diagnostic tests can improve compliance and efficiency. Operational research on promising developments like vaginal cleansing with antiseptics, vitamin A supplementation, and prophylactic antibiotics in high-risk women is needed.
Sepsis management continues to depend on good implementation of established technologies. Program-based approaches are required to improve uptake.