Sumida Masayuki, Taguchi Haruyoshi, Eguchi Kuniki, Kuroki Kazuhiko, Murakami Taro, Akimitsu Tomohide
Department of Neurosurgery, Hiroshima General Hospital, Hiroshima, Japan.
No Shinkei Geka. 2004 Mar;32(3):263-8.
Cerebellar hemangioblastoma develops alone or develops as part of von Hippel-Lindau disease. Moreover, multiple hemangioblastomas are found in 10-15%. It was reported that some hemangioblastomas recur with multiple recurrence in long time follow-up period. A 51 years old male was referred to our hospital because of headache and found a cerebellar tumor which was totally removed and diagnosed as hemangioblastoma pathologically. He presented no deficit after first surgery, but he did not come our hospital. In May 2000, he was referred to our hospital because of headache again and found five cerebellar tumors on MRI. Angiography showed markedly tumor stain. Retinal and spinal lesions were not seen. Two of five tumors was removed. The remaining three small tumors were received gamma knife surgery. In December 2000, because of cyst enlargement, one tumor was removed and the cyst was opened. In June 2001, he presented right hearing disturbance due to enlargement of cerebellar pontine angle tumor. The tumor was removed after tumor embolization, but hearing disturbance and slight dizziness remained. The remaining 5 mm tumor is followed.
小脑成血管细胞瘤可单独发生,或作为冯·希佩尔-林道病的一部分出现。此外,10%至15%的患者会出现多发成血管细胞瘤。据报道,一些成血管细胞瘤在长期随访中会多次复发。一名51岁男性因头痛被转诊至我院,发现小脑肿瘤,肿瘤被完整切除,病理诊断为成血管细胞瘤。首次手术后他没有出现功能缺损,但他没有再来我院。2000年5月,他因再次头痛被转诊至我院,MRI发现小脑有5个肿瘤。血管造影显示明显的肿瘤染色。未发现视网膜和脊髓病变。切除了5个肿瘤中的2个。其余3个小肿瘤接受了伽玛刀手术。2000年12月,由于囊肿增大,切除了1个肿瘤并打开了囊肿。2001年6月,由于小脑桥脑角肿瘤增大,他出现了右耳听力障碍。肿瘤栓塞后切除了肿瘤,但听力障碍和轻微头晕仍然存在。对剩余的5毫米肿瘤进行随访。