Suppr超能文献

糖尿病患者使用一种“草药”药物的利弊:病例报告

The advantages and disadvantages of a 'herbal' medicine in a patient with diabetes mellitus: a case report.

作者信息

Wood D M, Athwal S, Panahloo A

机构信息

Pharmacology and Clinical Pharmacology, Department of Basic Medical Sciences, St George's Hospital Medical School, London, UK.

出版信息

Diabet Med. 2004 Jun;21(6):625-7. doi: 10.1111/j.1464-5491.2004.01202.x.

Abstract

BACKGROUND

Patient-initiated alternative treatments in the management of chronic conditions are common and increasing in the United Kingdom. To date, there have been no reports of herbal medicine use alone in the management of diabetes mellitus. We report here the case of a man who attained excellent glycaemic control using a 'herbal' medicine and reveal how important it was to identify the products of active constituents.

CASE REPORT

A 48-year-old man attending our clinic in Tooting, South London with known Type 2 diabetes, with evidence of both micro- and macro-vascular diabetes-related complications, was poorly controlled despite a drug regimen consisting of oral metformin and twice daily insulin. He went to India for at least 1 year and on returning to the clinic had excellent glycaemic control off all diabetic medication. While away he had started himself on a regimen of three different 'herbal' balls. Samples of blood were found to contain chlorpropamide in a therapeutic concentration; chlorpropamide was also found in one of the balls. He has been counselled on the potential risks associated with chlorpropamide and his treatment reverted to a more conventional treatment regimen.

CONCLUSIONS

General practitioners and hospital physicians should be alert to those patients returning from abroad on effective 'herbal' medications that these may in fact contain an active ingredient.

摘要

背景

在英国,患者自行采用替代疗法治疗慢性病的情况很常见,且呈上升趋势。迄今为止,尚无仅使用草药治疗糖尿病的相关报道。在此,我们报告一例通过一种“草药”实现血糖良好控制的病例,并揭示识别活性成分产物的重要性。

病例报告

一名48岁男性,已知患有2型糖尿病,有微血管和大血管糖尿病相关并发症的证据,就诊于伦敦南部图廷的我们的诊所。尽管采用了口服二甲双胍和每日两次胰岛素的药物治疗方案,但血糖控制不佳。他前往印度至少一年,回到诊所时,在停用所有糖尿病药物的情况下血糖控制良好。在国外期间,他自行开始服用三种不同的“草药”丸剂。血液样本中发现含有治疗浓度的氯磺丙脲;在其中一种丸剂中也发现了氯磺丙脲。已就氯磺丙脲相关的潜在风险对他进行了咨询,其治疗恢复为更传统的治疗方案。

结论

全科医生和医院医生应警惕那些从国外带回有效“草药”药物的患者,这些药物可能实际上含有活性成分。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验