Wang Y, Zhang W G, Liu A R
Department of Oral Pathology, Ninth People's Hospital, School of Stomatology,Shanghai Second Medical University. Shanghai 200011, China.
Shanghai Kou Qiang Yi Xue. 1996 Sep;5(3):125-8.
A mass of the neck in an 8-year-old boy diagnosed with recurrent fetal cellular rhabdomyoma was reported.The recurrent tumor consisted of undifferentiated round and short spindle cells and immature striated muscle cells,which was similar to the primary tumor occured in five years ago.However,there were more large round myoblasts which mainly located at the periphery of the tumor and osteoid stroma in the recurrent case immuno-histochemistry stain and ultrstructure observation suggested that these were undifferntiated mesenchymal cell and myoblasts.The differential diagnosis from fibrosarcoma,highly differentiated rhabdomyosarcoma,and hemangiopericytoma were dicussed.Author considered FRMs has a recurrent and malignant change tendency though it belongs to benign tumor.
报告了一名8岁男孩颈部肿块,诊断为复发性胎儿细胞性横纹肌瘤。复发性肿瘤由未分化的圆形和短梭形细胞以及未成熟的横纹肌细胞组成,与5年前发生的原发性肿瘤相似。然而,复发病例中有更多的大圆形成肌细胞,主要位于肿瘤周边,还有类骨质基质。免疫组织化学染色和超微结构观察表明,这些是未分化的间充质细胞和成肌细胞。讨论了与纤维肉瘤、高分化横纹肌肉瘤和血管外皮细胞瘤的鉴别诊断。作者认为胎儿细胞性横纹肌瘤虽属良性肿瘤,但有复发和恶变倾向。