Leichsenring M, Hardenack M, Laryea M D
Division of Tropical Pediatrics, University Children's Hospital, Heidelberg, FRG.
Int J Vitam Nutr Res. 1992;62(2):181-5.
The relationship among the fatty acid (FA) composition of plasma cholesteryl esters (CE), plasma phospholipids (PL), total erythrocyte lipids, erythrocyte phosphatidylethanolamine (PE), erythrocyte phosphatidylcholine (PC), and total lipids of the subcutaneous fat (SCF) was investigated by parallel analyses of samples from 47 normally nourished German adults. Each lipid fraction revealed a characteristic FA pattern. A close relation between major FA in plasma lipids, especially in CE, and those in PC was found. The FA composition of PE, however, appeared to be more independent from plasma values. Of all FA in SCF only linoleic acid values showed a correlation to the values in CE and PC. It is concluded that, in clinical studies, FA analyses of total plasma lipids or total erythrocyte lipids fractions should be avoided in favour of separate analyses of various lipid fractions.
通过对47名营养正常的德国成年人的样本进行平行分析,研究了血浆胆固醇酯(CE)、血浆磷脂(PL)、总红细胞脂质、红细胞磷脂酰乙醇胺(PE)、红细胞磷脂酰胆碱(PC)和皮下脂肪(SCF)总脂质的脂肪酸(FA)组成之间的关系。每个脂质组分都显示出一种特征性的FA模式。发现血浆脂质中的主要FA,尤其是CE中的FA,与PC中的FA之间存在密切关系。然而,PE的FA组成似乎与血浆值更为独立。在SCF的所有FA中,只有亚油酸值与CE和PC中的值存在相关性。得出的结论是,在临床研究中,应避免对总血浆脂质或总红细胞脂质组分进行FA分析,而应优先对各种脂质组分进行单独分析。