Gentiloni N, Schiavino D, Della Corte F, Ricci E, Colosimo C
Istituto di Clinica Medica, Università Cattolica del Sacro Cuore, Policlinico A. Gemelli, Roma.
Ital J Neurol Sci. 1992 Jun;13(5):435-8. doi: 10.1007/BF02312151.
Altered cardiovascular and respiratory function is uncommonly encountered in multiple sclerosis, though it may appear late in the course of the disease [4]. Episodes of acute ventilatory failure due to autonomic and/or voluntary respiratory function paralysis have already been described. These episodes are often accompanied by a focal neurological deficit which expresses lesion at the level of the medulla [6]. A demyelinating bulbar lesion leading to altered cardiovascular function is likewise infrequent but when it happens, bradycardia, postural hypotension [2], or acute pulmonary edema without heart failure may occur [1]. We present a case of non cardiogenic acute pulmonary edema which had neither a toxic insult nor an infective agent as etiology, but appeared as the initial manifestation of a multifocal demyelinating syndrome.