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转移性神经母细胞瘤因视神经颅内受压导致双眼失明。

Metastatic neuroblastoma presenting with binocular blindness from intracranial compression of the optic nerves.

作者信息

Lau Juan J Chan, Trobe Jonathan D, Ruiz Robert E, Cho Robert W, Wechsler Daniel S, Shah Gaurang V, Gebarski Stephen S

机构信息

Department of Ophthalmology (Kellogg Eye Center), University of Michigan Medical School, Ann Arbor, Michigan 48105, USA.

出版信息

J Neuroophthalmol. 2004 Jun;24(2):119-24. doi: 10.1097/00041327-200406000-00005.

Abstract

A 2-year-old boy with blindness as an isolated symptom was found to have no light perception binocularly because of compression of both optic nerves by a neuroblastoma infiltrating the walls of the optic canals and medial sphenoid bone. Imaging disclosed a primary tumor near the kidney and multiple osseous metastases. Although neuroblastoma commonly causes blindness by metastasis to the orbit, it rarely causes bilateral blindness from intracranial compression of the optic nerves. This is the first report of bilateral blindness as the presenting feature.

摘要

一名2岁男孩以失明作为孤立症状,由于成神经细胞瘤浸润视神经管和蝶骨内侧壁导致双侧视神经受压,双眼无光感。影像学检查发现肾脏附近有原发性肿瘤和多处骨转移。虽然成神经细胞瘤通常通过转移至眼眶导致失明,但很少因颅内视神经受压引起双侧失明。这是首例以双侧失明为首发特征的报告。

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