一名儿童支原体肺炎感染表现为中性粒细胞减少、血小板减少和急性肝炎。

Mycoplasma pneumoniae infection presenting as neutropenia, thrombocytopenia, and acute hepatitis in a child.

作者信息

Chen Chun-Jung, Juan Chun-Jung, Hsu Mu-Ling, Lai Yuan-Sheng, Lin Shih-Peng, Cheng Shin-Nan

机构信息

Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheng-Kung Road, Section 2, Neihu, Taipei, Taiwan 114, ROC.

出版信息

J Microbiol Immunol Infect. 2004 Apr;37(2):128-30.

PMID:15181497

Abstract

Extrapulmonary manifestations of Mycoplasma pneumoniae pneumonia are uncommon and include hematologic, gastrointestinal, musculoskeletal, dermatologic, and neurologic complications. We report a case of serologically-confirmed M. pneumoniae infection complicated by severe neutropenia, thrombocytopenia, and hepatitis. The presence of antiplatelet and antineutrophil antibodies suggested that these autoantibodies caused the cytopenias. The disease had an acute course and the patient recovered after steroid treatment. This case indicates that neutropenia, thrombocytopenia and hepatitis are possible clinical manifestations of M. pneumoniae infection.

摘要

肺炎支原体肺炎的肺外表现并不常见，包括血液学、胃肠道、肌肉骨骼、皮肤和神经系统并发症。我们报告一例血清学确诊的肺炎支原体感染病例，该病例并发严重中性粒细胞减少、血小板减少和肝炎。抗血小板和抗中性粒细胞抗体的存在提示这些自身抗体导致了血细胞减少。该疾病病程呈急性，患者经类固醇治疗后康复。该病例表明中性粒细胞减少、血小板减少和肝炎可能是肺炎支原体感染的临床表现。