Manz Bertram
Arbeitsgruppe Magnetische Resonanz, Fraunhofer-Institut für Biomedizinische Technik, Ensheimer Strasse 48, 66386 St. Ingbert, Germany.
J Magn Reson. 2004 Jul;169(1):60-7. doi: 10.1016/j.jmr.2004.04.003.
A fast method for quantitative imaging of T2 and displacement (flow and diffusion) is presented. The pulse sequence combines multi-PGSE NMR with multi-echo acquisition and compensates for flow effects in the read gradient and diffusion during multi-echo trains. The impact of the gradient pulses in a multi-echo train on the signal phase and amplitude is discussed. It is shown that separate T2 and displacement images with microscopic resolution can be obtained within minutes. The capability for 3D flow imaging is demonstrated. The sequence is then used to investigate forced detachment of a biofilm in a tube.
本文提出了一种用于T2定量成像以及位移（流动和扩散）定量成像的快速方法。该脉冲序列将多脉冲梯度自旋回波核磁共振（multi-PGSE NMR）与多回波采集相结合，并在多回波序列期间补偿了读出梯度中的流动效应以及扩散效应。讨论了多回波序列中的梯度脉冲对信号相位和幅度的影响。结果表明，在数分钟内即可获得具有微观分辨率的T2和位移的单独图像。展示了三维流动成像的能力。然后使用该序列研究了管内生物膜的强制脱离。
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