Pier M P B I, Hulstijn W, Sabbe B G C
Department of Psychiatry, University Medical Centre, Reinier Postlaan 10, Nijmegen 6525 GC, The Netherlands.
J Affect Disord. 2004 Jul;81(1):73-7. doi: 10.1016/j.jad.2003.08.002.
The results of previous studies on psychomotor retardation (PR) in elderly depressed patients are inconsistent. The purpose of this study was (1) to try and establish whether elderly depressed patients show PR, and (2) if so, which process (cognitive/motor or both) is mainly slowed?
Twelve elderly depressed patients and healthy controls (age: 70) were compared on figure copying tasks in which the cognitive task difficulty was manipulated.
Both initiation time (IT) and movement time (MT) were prolonged in the patient group. The effects of the cognitive manipulations were not larger in the patient group.
The sample size was small. Furthermore, patients were not medication free.
A cognitive and a more pronounced motor retardation was found. Clinicians should be aware of this at least additive effect of aging and depression on PR in elderly patients.
先前关于老年抑郁症患者精神运动迟缓(PR)的研究结果并不一致。本研究的目的是:(1)试图确定老年抑郁症患者是否存在精神运动迟缓;(2)如果存在,主要是哪个过程(认知/运动或两者)变慢?
对12名老年抑郁症患者和健康对照者(年龄:70岁)进行图形临摹任务比较,其中认知任务难度是经过操控的。
患者组的起始时间(IT)和运动时间(MT)均延长。认知操控对患者组的影响并不更大。
样本量小。此外,患者并非未服用药物。
发现存在认知和更明显的运动迟缓。临床医生应意识到衰老和抑郁对老年患者精神运动迟缓至少具有累加效应。