Hammar Mats, Nedstrand Elizabeth, Wyon Yvonne
Avdelningen för obstetrik och gynekologi, Hälsouniversitetet, Linköping.
Lakartidningen. 2004 Apr 29;101(18):1612-6.
Vasomotor symptoms with hot flushes and sweating are reported by about 75 percent of women around menopause. Hormone replacement therapy (HRT) is the treatment of choice but some women have medical contraindications or side effects. There is, therefore, a need of alternative therapies. Progestagens may decrease hot flushes, as will clonidin and selective serotonin reuptake inhibitors. Phytoestrogens, which exist in some dietary products and complementary and alternative medicines have estrogen-like effects and may decrease hot flushes, although there are contradictory scientific reports. Acupuncture, exercise and behavioral therapy may also decrease vasomotor symptoms. No alternative therapy is as effective as HRT.
约75%的绝经前后女性会出现潮热和出汗等血管舒缩症状。激素替代疗法(HRT)是首选治疗方法,但一些女性存在医学上的禁忌证或副作用。因此,需要替代疗法。孕激素、可乐定和选择性5-羟色胺再摄取抑制剂可能会减轻潮热。存在于一些饮食产品以及补充和替代药物中的植物雌激素具有类雌激素作用,可能会减轻潮热,不过也有相互矛盾的科学报道。针灸、运动和行为疗法也可能减轻血管舒缩症状。没有哪种替代疗法能像激素替代疗法那样有效。