Jones Susan
Department of Biochemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK.
Genome Biol. 2004;5(6):226. doi: 10.1186/gb-2004-5-6-226. Epub 2004 May 28.
The basic helix-loop-helix proteins are dimeric transcription factors that are found in almost all eukaryotes. In animals, they are important regulators of embryonic development, particularly in neurogenesis, myogenesis, heart development and hematopoiesis.
基本螺旋-环-螺旋蛋白是几乎在所有真核生物中都能找到的二聚体转录因子。在动物中,它们是胚胎发育的重要调节因子,尤其在神经发生、肌发生、心脏发育和造血过程中。