Kobori Go, Yamada Hitosi, Hirai Sinji, Higashi Yoshihito
Department of Urology, Ijinnkai Takeda General Hospital.
Hinyokika Kiyo. 2004 Apr;50(4):279-81.
A 70-year-old man was admitted with slight dyspnea and fever up. The patient had had total cystectomy for urothelial carcinoma of urinary bladder 14 months earlier and had a ureterocutaneostomy. At 2 days after the admission, he had a sudden attack of dyspnea. He was transferred to the intensive care unit, and mechanical ventilation was initiated. The pulmonary arterial pressure was measured at 65/30 mmHg, but the etiology for the pulmonary hypertension was unclear. Although highly suggestive of pulmonary embolism, chest roentgenogram and chest computed tomography (CT) showed clear lung fields. Pulmonary angiography disclosed no evidence of embolism. Despite anticoagulation therapy he died of respiratory failure. Autopsy revealed diffuse microscopic pulmonary tumor embolism with urothelial cacinoma in the pulmonary arterial vasculature. Microscopic pulmonary tumor embolism has rarely been reported with urothelial carcinoma.
一名70岁男性因轻度呼吸困难和发热入院。该患者14个月前因膀胱尿路上皮癌接受了全膀胱切除术,并进行了输尿管皮肤造口术。入院后第2天,他突然发作呼吸困难。他被转入重症监护病房,并开始进行机械通气。测得肺动脉压为65/30 mmHg,但肺动脉高压的病因尚不清楚。尽管高度怀疑肺栓塞,但胸部X线片和胸部计算机断层扫描(CT)显示肺部清晰。肺血管造影未发现栓塞证据。尽管进行了抗凝治疗,他仍死于呼吸衰竭。尸检显示在肺动脉血管系统中有弥漫性微观肺肿瘤栓塞伴尿路上皮癌。微观肺肿瘤栓塞很少见有尿路上皮癌的报道。