Li Dong-Ming, Xu Bo, Xu Xiao-Na
Department of Radiotherapy, School of Oncology, Peking University, Beijing Institute for Cancer Research, Beijing Cancer Hospital, Beijing, PR China.
Ai Zheng. 2004 Jun;23(6):722-3.
BACKGROUND & OBJECTIVE: The amount of patients implanted with permanent cardiac pacemaker is increasing, among whom some tumor patients require radiotherapy. This retrospective study summarized experience of the radiotherapy of tumor patients implanted with the permanent cardiac pacemaker and evaluated the results of the radiotherapy.
Four patients (2 male, 2 female; age range 70-81 years) implanted with permanent cardiac pacemaker were studied. Among them, 3 had third-degree atria ventricular block (AVB) and were implanted with VVI pacemakers, and 1 sick sinus syndrome (SSS), and was implanted with DDDR packmaker. Pathological study proved 1 esophageal carcinoma, 1 non-Hodgkin's lymphoma, 1 non-small cell lung carcinoma, and 1 nasopharyngeal carcinoma. 60Co or 6-8 MV linear accelerator 40-70 Gy were used to irradiate, while the dynamic electrocardiogram was monitored through the radiation period.
All 4 patients completed the radiotherapy. 3 cases gained PR and 1 case gained SD; 3 patients received continuous chemotherapy, 1 patient received a second radiotherapy. The monitor of dynamic electrocardiogram enunciation for 10 months revealed good function of the cardiac pacemakers.
With proper choice of irradiation energy and dose, according to irradiation field including the pacemaker and contents or not, 4 tumor patients implanted with permanent cardiac pacemaker could tolerate radiotherapy well, and the cardiac pacemaker could function normally.
植入永久性心脏起搏器的患者数量不断增加,其中部分肿瘤患者需要接受放射治疗。本回顾性研究总结了植入永久性心脏起搏器的肿瘤患者放射治疗的经验,并评估了放射治疗的效果。
研究4例植入永久性心脏起搏器的患者(男2例,女2例;年龄70 - 81岁)。其中3例为三度房室传导阻滞(AVB),植入VVI起搏器;1例为病态窦房结综合征(SSS),植入DDDR起搏器。病理检查证实1例为食管癌,1例为非霍奇金淋巴瘤,1例为非小细胞肺癌,1例为鼻咽癌。采用60Co或6 - 8 MV直线加速器给予40 - 70 Gy照射,放疗期间监测动态心电图。
4例患者均完成放疗。3例获部分缓解(PR),1例获疾病稳定(SD);3例患者接受持续化疗,1例患者接受二次放疗。动态心电图监测10个月显示心脏起搏器功能良好。
通过合理选择照射能量和剂量,根据照射野是否包括起搏器及其内容物,4例植入永久性心脏起搏器的肿瘤患者能够很好地耐受放疗,且心脏起搏器能正常工作。