Nuttall Michaela
Bromley Primary Care Trust.
Nurs Times. 2004;100(21):28-9.
Coronary heart disease (CHD) is the UK's biggest killer. While recommending that all patients can benefit from lifestyle interventions, the current guidelines focus pharmacological management on those at high risk. An over the counter (OTC) statin would enable people with moderate (10-15 per cent) CHD risk to take preventive action. Pharmacists would be able to recommend OTC simvastatin to those at moderate risk by following a simple pharmacy protocol to assess a person's risk. A regime of 10 mg simvastatin daily would have a significant impact on both the low-density lipoprotein cholesterol (LDL-C) level and the CHD risk of those at moderate risk. Cholesterol testing would not be mandatory but would be available in pharmacy to enable people to monitor their progress.
冠心病是英国最大的杀手。虽然建议所有患者都能从生活方式干预中受益,但目前的指南将药物治疗重点放在高危人群上。非处方(OTC)他汀类药物将使冠心病风险为中度(10%-15%)的人群能够采取预防措施。药剂师可以通过遵循简单的药房规程来评估一个人的风险,从而向中度风险人群推荐非处方辛伐他汀。每天服用10毫克辛伐他汀的方案将对中度风险人群的低密度脂蛋白胆固醇(LDL-C)水平和冠心病风险产生重大影响。胆固醇检测并非强制要求,但药房可提供此项检测,以便人们监测自身进展。