McArthur David L, Chute Dennis J, Villablanca J Pablo
Division of Neurosurgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095-1752, USA.
Brain Pathol. 2004 Apr;14(2):185-94. doi: 10.1111/j.1750-3639.2004.tb00052.x.
This article examines 3 contexts in which moderate or severe traumatic brain injury can be approached. The epidemiologic background of moderate and severe traumatic brain injury is presented, with particular attention paid to new findings from the study of a national hospital inpatient database. We review aspects of neuroimaging and how new imaging modalities can reveal fine detail about traumatic brain injury. Finally we examine the current state of neuropathologic evaluation of, and recent developments in, understanding of the neural disruptions that occur following traumatic brain injury, together with cellular reactions to these disruptions.
本文探讨了应对中度或重度创伤性脑损伤的三种情况。介绍了中度和重度创伤性脑损伤的流行病学背景,特别关注了对国家医院住院患者数据库研究的新发现。我们回顾了神经影像学的各个方面,以及新的成像方式如何揭示创伤性脑损伤的细微细节。最后,我们研究了创伤性脑损伤后神经病理学评估的现状,以及对神经破坏的理解方面的最新进展,以及细胞对这些破坏的反应。