一只五个月大的海狸（加拿大海狸）患全身性弓形虫病。

Systemic toxoplasmosis in a five-month-old beaver, (Castor canadensis).

作者信息

Forzán María J, Frasca Salvatore

机构信息

Department of Pathobiology and Veterinary Science, University of Connecticut, U-3089, 61 North Eagleville Road, Storrs, Connecticut 06269, USA.

出版信息

J Zoo Wildl Med. 2004 Mar;35(1):113-5. doi: 10.1638/03-031.

DOI:10.1638/03-031

PMID:15193086

Abstract

A 5-mo-old orphan beaver, Castor canadensis, died of severe systemic toxoplasmosis during rehabilitation. Histologic lesions included lymphohistiocytic encephalitis, myocarditis, and interstitial pneumonia with multinucleated cells. Intracytoplasmic cysts containing tachyzoites and bradyzoites identified as Toxoplasma gondii by immunohisto-chemistry were present in macrophages, type-II pneumocytes, and endothelial cells. Immunohistochemistry using a polyclonal morbillivirus antibody and transmission electron microscopy of lung revealed no evidence of concurrent paramyxoviral infection, as commonly found in carnivores with toxoplasmosis. Toxoplasmosis may affect young beavers in rehabilitation and zoological settings.

摘要

一只5个月大的加拿大河狸孤儿在康复期间死于严重的全身性弓形虫病。组织学病变包括淋巴细胞性组织细胞性脑炎、心肌炎和伴有多核细胞的间质性肺炎。通过免疫组织化学鉴定为刚地弓形虫的含有速殖子和缓殖子的胞浆内囊肿存在于巨噬细胞、II型肺泡上皮细胞和内皮细胞中。使用多克隆麻疹病毒抗体的免疫组织化学和肺组织的透射电子显微镜检查未发现同时存在副粘病毒感染的证据，而副粘病毒感染在患弓形虫病的食肉动物中很常见。弓形虫病可能影响康复期的幼河狸以及动物园环境中的河狸。