觉醒与注意力相遇之处：一项功能磁共振成像和脑电图同步记录研究。

Where arousal meets attention: a simultaneous fMRI and EEG recording study.

作者信息

Foucher J R, Otzenberger H, Gounot D

机构信息

Clinique Psychiatrique, Hôpitaux Universitaires, BP 406-67091 Strasbourg Cedex, France.

出版信息

Neuroimage. 2004 Jun;22(2):688-97. doi: 10.1016/j.neuroimage.2004.01.048.

DOI:10.1016/j.neuroimage.2004.01.048

PMID:15193597

Abstract

In this fMRI study, we looked for the regions supporting interaction between cortical arousal and attention during three conditions: detection, observation, and rest. Arousal measurements were obtained from the EEG low-frequency (LF) power (5-9.5 Hz) recorded continuously together with fMRI. Whatever the condition, arousal was positively correlated with the fMRI signal of the right dorsal-lateral prefrontal and superior parietal cortices, closely overlapping regions involved in the maintenance of attention. Although the inferior temporal areas also presented a correlation with arousal during detection, path analysis suggests that this influence may be indirect, through the top-down influence of the previously mentioned network. However, those visual-processing areas could account for the correlation between arousal and performances. Lastly, the medial frontal cortex, frontal opercula, and thalamus were inversely correlated with arousal but only during detection and observation so that they could account for the control of arousal.

摘要

在这项功能磁共振成像（fMRI）研究中，我们在三种状态下寻找支持皮质唤醒与注意力之间相互作用的区域：检测、观察和休息。唤醒测量值是通过与fMRI同步连续记录的脑电图低频（LF）功率（5 - 9.5赫兹）获得的。无论处于何种状态，唤醒与右侧背外侧前额叶和顶上叶皮质的fMRI信号呈正相关，这些区域紧密重叠，参与注意力的维持。尽管颞下区域在检测过程中也与唤醒存在相关性，但路径分析表明，这种影响可能是间接的，是通过上述网络的自上而下的影响。然而，那些视觉处理区域可能解释了唤醒与表现之间的相关性。最后，内侧额叶皮质、额下回和丘脑与唤醒呈负相关，但仅在检测和观察期间如此，因此它们可能参与唤醒的控制。